SAB4300738

Anti-Collagen IV antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): ALPHA-1 CHAIN ARRESTEN, COL4A1 NC1 domain, COLLAGEN OF BASEMENT MEMBRANE, alpha 1 type IV collagen preproprotein, collagen IV alpha-1 polypeptide
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: 160 kDa
• reatividade de espécies: mouse, human
• concentração: 1.0 mg/mL
• técnica(s): immunohistochemistry: 1:50-1:100; western blot: 1:500-1:3000 (Cell Lysate)
• Isotipo: IgG
• nº de adesão: NP_001836.2
• nº de adesão UniProt: P02462
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... COL4A1(1282)

Descrição

Descrição geral

COL4A1 (collagen type IV α 1 chain) belongs to the collagen family. It has an N-terminal 7S domain, a C-terminal globular domain (NC1), and the central triple helical part with short interruptions of the Gly-X-Y repeats. It is an important constituent of type IV collagen in the basement membrane. The COL4A1 gene is located on human chromosome 13q34.

Especificidade

The antibody detects endogenous levels of total Collagen IV protein.

Imunogênio

Synthesized peptide derived from human Collagen IV.

Aplicação

Collagen Type IV from human cell culture has been used in immunofluorescent analysis.

Ações bioquímicas/fisiológicas

COL4A1 (collagen type IV α 1 chain) related disorder is associated with pulmonary complication. Mutations in COL4A1 result in familial porencephaly, infantile hemiplegia, cerebral small vessel disease (CSVD) and hemorrhagic stroke.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable