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Merck
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Documentos Principais

S8260

Sigma-Aldrich

Salbutamol

≥96% (GC), powder, β2 adrenoceptor agonist

Sinônimo(s):

α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α′-diol, Albuterol

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About This Item

Fórmula empírica (Notação de Hill):
C13H21NO3
Número CAS:
Peso molecular:
239.31
Beilstein:
6405698
Número CE:
Número MDL:
Código UNSPSC:
12352200
ID de substância PubChem:
NACRES:
NA.77

Nome do produto

Salbutamol,

Nível de qualidade

solubilidade

methanol: complete 50 mg/ml, clear, colorless to yellow

originador

GlaxoSmithKline

cadeia de caracteres SMILES

CC(C)(C)NCC(O)c1ccc(O)c(CO)c1

InChI

1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3

chave InChI

NDAUXUAQIAJITI-UHFFFAOYSA-N

Informações sobre genes

human ... ADRB2(154)

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Aplicação

Salbutamol was administered to primate model to study the bronchoconstriction in chronic allergic asthma.20 Salbutamol was used as a standard for rapid pharmacokinetic screening of human plasma samples using HPLC.21

Ações bioquímicas/fisiológicas

β2-adrenoceptor agonist
Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).1 Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.2

Características e benefícios

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1B

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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