Pular para o conteúdo
Merck
Todas as fotos(5)

Key Documents

View All Documentation

P6001

Sigma-Aldrich

p-Phenylenediamine

98% (GC)

Sinônimo(s):

1,4-Benzenediamine, 1,4-Diaminobenzene, 1,4-Phenylenediamine

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(5)

About This Item

Fórmula linear:
C6H4(NH2)2
Número CAS:
106-50-3
Peso molecular:
108.14
Beilstein:
742029
Número CE:
203-404-7
Número MDL:
MFCD00007901
Código UNSPSC:
12352204
ID de substância PubChem:
24898724
NACRES:
NA.83

densidade de vapor

3.7 (vs air)

Nível de qualidade

200

pressão de vapor

1.08 mmHg ( 100 °C)

descrição

anti-fade reagent

Ensaio

98% (GC)

pb

267 °C (lit.)

pf

138-143 °C (lit.)

cadeia de caracteres SMILES

Nc1ccc(N)cc1

InChI

1S/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H2

chave InChI

CBCKQZAAMUWICA-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Aplicação

p-Phenylenediamine has been used:
  • to evaluate its sensitization potential in vitro in langerhans-like dendritic cells and autologous T cells
  • to treat the dorsal sides of the ears of mice, to study its systemic immunological effects
  • in glycerol to coverslip coronal sections in the attempt to count Aβ plaques

Anti-fade reagent is added to the mounting medium in fluorescence microscopy to retard photobleaching of fluorescein and other fluorescent dyes.

Ações bioquímicas/fisiológicas

p-Phenylenediamine causes allergic reactions with skin. It is widely used in hair dyes. It eventually forms Bandrowski′s base, which is found to be the primary cause for allergy. p-Phenylenediamine exposure results in dermatitis, urticaria and anaphylaxis. It acts as an electron donor and is known to reduce cytochrome c.

Atenção

Darkens in storage.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 1 Oral

Órgãos-alvo

Kidney,Heart,Musculo-skeletal system

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

230.0 °F - closed cup

Ponto de fulgor (°C)

110 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 4

1 of 4

Terephthaloyl chloride ≥99%, flakes

Sigma-Aldrich

120871

Terephthaloyl chloride

1,3-Phenylenediamine for synthesis

Sigma-Aldrich

8.20991

1,3-Phenylenediamine

1,4-Phenylenediamine-15N2 98 atom % 15N

Sigma-Aldrich

487465

1,4-Phenylenediamine-15N2

1,4-Phenylenediamine-2,3,5,6-d4 98 atom % D

Sigma-Aldrich

487473

1,4-Phenylenediamine-2,3,5,6-d4

p-Phenylenediamine
DeLeo VA
Dermatitis : Contact, Atopic, Occupational, Drug : Official Journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group, 17(2), 53-55 (2006)
Ying-Zhi Xu et al.
NAR cancer, 2(4), zcaa029-zcaa029 (2020-10-24)
Diffuse large B-cell lymphoma (DLBCL) is a molecularly heterogeneous group of malignancies with frequent genetic abnormalities. G-quadruplex (G4) DNA structures may facilitate this genomic instability through association with activation-induced cytidine deaminase (AID), an antibody diversification enzyme implicated in mutation of
p-Phenylenediamine allergy: the role of Bandrowski's base
White JML, et al.
Clinical and Experimental Allergy, 36(10), 1289-1293 (2006)
In vitro evaluation of the sensitization potential of weak contact allergens using Langerhans-like dendritic cells and autologous T cells
Rougier N, et al.
Toxicology, 145(1), 73-82 (2000)
Identification and quantification of para-phenylenediamine in a temporary black henna tattoo
Brancaccio RR, et al.
American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society, 13(1), 15-18 (2002)
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica