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Key Documents

P4538

Sigma-Aldrich

Poli-L-ornitina

suitable for cell culture, Mol wt 5,000-15,000

Sinônimo(s):

L-Ornithine homopolymer hydrobromide

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
12352209
NACRES:
NA.26

product name

Poli-L-ornitina, mol wt 5,000-15,000

forma

powder

Nível de qualidade

peso molecular

5,000-15,000

técnica(s)

cell culture | mammalian: suitable

cor

white to off-white

temperatura de armazenamento

−20°C

InChI

1S/C5H12N2O2.BrH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H

chave InChI

GWRQMKDBBHFVIZ-UHFFFAOYSA-N

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Aplicação


  • Thermodynamic Characterization of Polypeptide Complex Coacervation.: The research investigates the thermodynamic properties of polypeptide complex coacervation, including the role of Poly-L-ornithine hydrobromide in these interactions. This study provides insights into the self-assembly processes of polypeptides, which are crucial for designing new biomaterials (Priftis et al., 2012).

Nota de análise

Molecular weight based on viscosity.

Outras notas

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificados de análise (COA)

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International journal of pharmaceutics, 210(1-2), 97-107 (2001-02-13)
The impetus to develop non-viral gene delivery vectors has led to examination of synthetic polycationic polymers as plasmid DNA (pDNA) condensing agents. Previous reports have highlighted superiority (up to x 10-fold) in the in-vitro transfection of pDNA complexes formed by
J P McQuilling et al.
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Severe hypoxia caused by a lack of vascular supply and an inability to retrieve encapsulated islets transplanted in the peritoneal cavity for biopsy and subsequent evaluation are obstacles to clinical application of encapsulation strategies for islet transplantation. We recently proposed
Electrophoretic deposition of chiral polymers and composites.
Wang Y, Pang X, Zhitomirsky I.
Colloids and Surfaces, B: Biointerfaces, 87, 505-509 (2011)
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Gene transfer vectors formed between the cationic polyamino acid, poly-(L)-omithine (PLO) and plasmid DNA (pDNA) have demonstrated superior transfection efficiency (up to x 10-fold) compared to equivalent polylysine-based systems in-vitro. The mechanism(s) underlying this observation remains to be elucidated. We
S K Tam et al.
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Artigos

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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