P1034

Phenyl isothiocyanate

Sigma Grade, 8.36 M, suitable for solid phase protein sequencing analysis, ≥99% (GC), liquid

• Sinônimo(s): PITC
• Fórmula linear: C₆H₅NCS
• Número CAS: 103-72-0
• Peso molecular: 135.19
• Beilstein: 471392
• Número CE: 203-138-1
• Número MDL: MFCD00004798
• Código UNSPSC: 12352118
• ID de substância PubChem: 24898144
• NACRES: NA.31

Propriedades

• grau: Sigma Grade
• Nível de qualidade: 100
• Ensaio: ≥99% (GC)
• Formulário: liquid
• concentração: 8.36 M
• índice de refração: n20/D 1.6515 (lit.)
• p.e.: 218 °C (lit.)
• pf: −21 °C (lit.)
• densidade: 1.132 g/mL at 20 °C (lit.)
• adequação: suitable for solid phase protein sequencing analysis
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: S=C=Nc1ccccc1
• InChI: 1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H
• chave InChI: QKFJKGMPGYROCL-UHFFFAOYSA-N

Descrição

Descrição geral

Phenyl isothiocyanate belongs to the class of aromatic compounds with isothiocyanate groups. It is typically used as a precolumn derivatization agent for the formation of phenylthiocarbamyl amino acids for their subsequent determination using chromatography techniques.

Aplicação

Phenyl isothiocyanate may be used in the polypeptide and protein sequencing at the subpicomole and subnanomole levels, respectively, by applying automated Edman chemistry followed by the analysis using high-performance liquid chromatography (HPLC) technique.

Derivatizing reagent for primary and secondary amines. Used in sequencing peptides by Edman degradation and in amino acid analyses by HPLC.

Embalagem

One mL size packaged in flame sealed amber ampules under argon.
Ten mL size packaged in screw cap amber vials under argon.

Informações de segurança

• Pictogramas: GHS06,GHS08,GHS05
• Palavra indicadora: Danger
• Frases de perigo: H301,H314,H317,H334
• Declarações de precaução: P261 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 3 Oral - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 190.4 °F - closed cup
• Ponto de fulgor (°C): 88 °C - closed cup
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter