L5418
Lipopolissacarídeos
Ready Made solution, 1 mg/mL
Sinônimo(s):
LPS
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About This Item
Produtos recomendados
fonte biológica
Escherichia coli (O55:B5)
Nível de qualidade
Formulário
aqueous solution
concentração
1 mg/mL
cor
white to faint yellow
solubilidade
water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
Condições de expedição
wet ice
temperatura de armazenamento
2-8°C
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Descrição geral
This product is a 0.2 um filtered aqueous solution containing 1 mg/mL of lipopolysaccharides (LPS) from E. coli serotype O55:B5. The source strain is CDC 1644-70. This LPS serotype has been used in studies of septic shock and to induce myocarditis.
Aplicação
Os lipopolissacarídeos (LPSs) são componentes característicos da parede celular de bactérias gram negativas. Os LPS e sua porção lipídica A estimulam as células do sistema imunológico inato através do receptor do tipo Toll 4 (TLR4), um membro da família de proteínas do receptor do tipo Toll 4 que reconhece patógenos comuns associados a padrões moleculares (PAMPs).
Ações bioquímicas/fisiológicas
Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.
Nota de preparo
The LPS used to prepare the solution have been phenol-extracted and chromatographically purified by gel filtration. Lipopolysaccharides prepared by phenol extraction contain up to 60% RNA and less than 1% protein. Subsequent purification by gel filtration chromatography removes much of protein present in the phenol-extracted LPS, but leaves a product that still contains 10-20% nucleic acids. Further purification using ion exchange chromatography yields an LPS product which contains <1% protein and <1% RNA.
Outras notas
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
produto relacionado
Nº do produto
Descrição
Preços
Código de classe de armazenamento
12 - Non Combustible Liquids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Conteúdo relacionado
Lipopolysaccharide (LPS) is the major component of the outer membrane of Gram-negative bacteria. Lipopolysaccharide is localized in the outer layer of the membrane and is, in noncapsulated strains, exposed on the cell surface.
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