L4516
Lipopolysaccharides from Escherichia coli O127:B8
BioXtra, suitable for cell culture, γ-irradiated
Sinônimo(s):
LPS
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About This Item
Produtos recomendados
fonte biológica
Escherichia coli (O127:B8)
Nível de qualidade
esterilidade
γ-irradiated
linha de produto
BioXtra
Formulário
lyophilized powder
purificado por
gel-filtration chromatography
técnica(s)
cell culture | mammalian: suitable
Impurezas
<1% Protein (Lowry)
solubilidade
H2O: 5 mg/mL, slightly hazy
temperatura de armazenamento
2-8°C
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Aplicação
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Lipopolysaccharides from Escherichia coli 0127:B8 has been used:
- to study the LPS-induced macrophage survival in mice
- to elicit the secretion of cytokines by cattle PBMC
- to study apoptosis of highly susceptible macrophage cells in a LPS-induced proinflammatory environment
- to perform autophagy assay in BV2 and BV2-LC3 cells
- for stimulation of human monocytes, macrophages and mouse microglia cells
- to induce pentraxin-3 expression in 293T cells
Ações bioquímicas/fisiológicas
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4). Being an immunogenic antigen, it enhances immune responses to soluble antigens.
Reconstituição
Lipopolysaccharides are supplied as lyophilized, γ-irradiated powders. To reconstitute, add 1 ml sterile balanced salt solution or tissue culture medium to the vial (1 mg) and gently swirl until the powder dissolves. Reconstituted product may be further diluted to desired working concentrations using sterile balanced salt solution or tissue culture medium.
Outras notas
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Nº do produto
Descrição
Preços
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 2 Oral
Código de classe de armazenamento
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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