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L5000

Sigma-Aldrich

N-Lauroylsarcosine, neat

≥95%

Sinônimo(s):

N-Dodecanoyl-N-methylglycine, Sarkosyl L

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About This Item

Fórmula linear:
CH3(CH2)10CON(CH3)CH2COOH
Número CAS:
97-78-9
Peso molecular:
271.40
Número CE:
202-608-3
Número MDL:
MFCD00021749
Código UNSPSC:
12161900
ID de substância PubChem:
24896382
NACRES:
NA.21

descrição

anionic

Nível de qualidade

200

Ensaio

≥95%

peso molecular

average mol wt 600

número de agregação

2

CMC

14.6

cadeia de caracteres SMILES

CCCCCCCCCCCC(=O)N(C)CC(O)=O

InChI

1S/C15H29NO3/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19/h3-13H2,1-2H3,(H,18,19)

chave InChI

BACYUWVYYTXETD-UHFFFAOYSA-N

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Descrição geral

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

forma física

May be liquid at room temperature

Pictogramas

Skull and crossbonesCorrosion
GHS06,GHS05

Palavra indicadora

Danger

Frases de perigo

H315,H318,H330

Classificações de perigo

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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N-Lauroilsarcosina European Pharmacopoeia (EP) Reference Standard

Y0001772

N-Lauroilsarcosina

Sarcosine 98%

Sigma-Aldrich

131776

Sarcosine

Sulfato de dextrana avg mol wt >500,000 (dextran starting material)

Sigma-Aldrich

D8787

Sulfato de dextrana

Proteose-Peptone suitable for microbiology

Millipore

82450

Proteose-Peptone

Tiocianato de guanidina for molecular biology, ≥99%

Sigma-Aldrich

G9277

Tiocianato de guanidina

Tiocianato de guanidina ≥97% (titration)

Sigma-Aldrich

G6639

Tiocianato de guanidina

Desoxicolato de sódio ≥97% (titration)

Sigma-Aldrich

D6750

Desoxicolato de sódio

Reagente de bloqueio For nucleic acid hybridization and detection

Roche

11096176001

Reagente de bloqueio

Manganese(II) chloride solution BioReagent, for molecular biology, storage temp.:room temp

Sigma-Aldrich

M1787

Manganese(II) chloride solution

Roslyn N Brown et al.
Journal of proteome research, 9(9), 4454-4463 (2010-08-10)
A simple and effective subcellular proteomic method for fractionation based on osmotic lysis, differential centrifugation, and Sarkosyl solubilization was applied to the Gram-negative bacterium Shewanella oneidensis to gain insight into its subcellular architecture. Global differences in bacterial cytoplasm, inner membrane
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 285(29), 22221-22231 (2010-04-21)
More than 100 different mutations in Cu,Zn-superoxide dismutase (SOD1) are linked to a familial form of amyotrophic lateral sclerosis (fALS). Pathogenic mutations facilitate fibrillar aggregation of SOD1, upon which significant structural changes of SOD1 have been assumed; in general, however
Kunie Ando et al.
The American journal of pathology, 178(2), 803-816 (2011-02-02)
Many models of human tauopathies have been generated in mice by expression of a human mutant tau with maintained expression of mouse endogenous tau. Because murine tau might interfere with the toxic effects of human mutant tau, we generated a
Jocelyne Piret et al.
Antimicrobial agents and chemotherapy, 46(9), 2933-2942 (2002-08-17)
The mechanisms of herpes simplex virus (HSV) inactivation by sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), two anionic surfactants with protein denaturant potency, have been evaluated in cultured cells. Results showed that pretreatment of HSV type 1 (HSV-1) strain F
Yoshiaki Furukawa et al.
The Journal of biological chemistry, 286(21), 18664-18672 (2011-04-02)
The transactivation response element (TAR) DNA-binding protein-43 (TDP-43) is a nuclear protein that normally regulates transcription and splicing. Abnormal accumulation of insoluble inclusions containing TDP-43 has been recently reported in the affected tissues of amyotrophic lateral sclerosis (ALS) patients. Here
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