G5419

Anti-GAD1/GAD2 Antibody

mouse monoclonal, K-87

• Sinônimo(s): Anti-GAD 67
• Número MDL: MFCD06202147
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• Nome do produto: Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse, clone K-87, purified antibody
• fonte biológica: mouse
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: purified antibody
• tipo de produto de anticorpo: primary antibodies
• clone: K-87, monoclonal
• peso molecular: antigen 67 kDa
• reatividade de espécies: rat, mouse, human
• concentração: ~1 mg/mL
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:20,000 (with antigen-retrieval step); western blot: 1:500-1:20,000 using mouse brain extract
• Isotipo: IgG1κ
• nº de adesão UniProt: Q99259
• Condições de expedição: dry ice
• temperatura de armazenamento: −70°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... GAD1(2571) ; mouse ... Gad1(14415) ; rat ... Gad1(24379)

Descrição

Descrição geral

Glutamic Acid Decarboxylase 67 (GAD67) is encoded by the gene glutamic acid decarboxylase 1 (GAD1). GAD1 gene is located on the human chromosome at 2q31.1. GAD67 is localized in the dendrites and cell bodies.

Especificidade

Reacts specifically with GAD67. Does not crossreact with GAD65.

Imunogênio

This peptide does not share homology with GAD65.

synthetic peptide from mouse GAD67 (amino acids 87-106).

Aplicação

Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody is suitable for use in immunoblot, western blot (at 1:500-1:20,000 dilutions using mouse brain extract) and immunohistochemistry (at 1:500-1:20,000 dilutions in mouse brain sections).

Monoclonal anti-glutamic acid decarboxylase 67 (GAD67) antibody produced in mouse has been used in:

• immunohistofluorescence
• western blotting
• immunohistochemistry.

Ações bioquímicas/fisiológicas

Glutamic Acid Decarboxylase 67 (GAD67) is involved in the production of γ-amino butyric acid (GABA), a inhibitory neurotransmitter in the central nervous system (CNS). Deficiency of GAD67 leads to psychosis, schizophrenia and bipolar diseases.

forma física

Solution in phosphate buffered saline containing 0.01% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)