F3388

Ferric citrate

BioReagent, suitable for cell culture

• Sinônimo(s): Iron(III) citrate, Iron(III) citrate hydrate
• Fórmula empírica (Notação de Hill): C₆H₅FeO₇
• Número CAS: 3522-50-7
• Peso molecular: 244.94
• Número CE: 222-536-6
• Número MDL: MFCD00013098
• Código UNSPSC: 12352205
• ID de substância PubChem: 24894843
• NACRES: NA.75

Propriedades

• fonte biológica: synthetic (organic)
• linha de produto: BioReagent
• técnica(s): cell culture | mammalian: suitable
• solubilidade: hot water: 0.01 g/mL, clear, orange-yellow
• Condições de expedição: ambient
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: OC12CC(=O)O[Fe](OC(=O)C1)OC2=O
• InChI: 1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3
• chave InChI: NPFOYSMITVOQOS-UHFFFAOYSA-K

Descrição

Aplicação

Ferric citrate provides a source of iron used in cell culture applications. It provides iron in a less toxic form than free iron salts. Ferric citrate has been used as medium supplement in human osteosarcoma cell (U2OS) culture, human embryonic kidney (HEK293) cells and adult primary cardiomyocytes.

Ações bioquímicas/fisiológicas

Ferric citrate is used as a component of protein-free medium. It is used as a substitute for transferrin in mouse hybridomas culture. Ferric citrate enhances IgM production. It indirectly stimulates the mitogen-activated protein kinase (MAPK) by favoring high amphiregulin oncoprotein levels in colon cancer.  Ferric citrate is effective in binding to phosphate in patients with dialysis-dependent chronic kidney disease.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)