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C2776

Sigma-Aldrich

Tetrafluoroborato de 1-ciano-dimetilaminopiridínio

organic cyanylating reagent

Sinônimo(s):

CDAP

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About This Item

Fórmula empírica (Notação de Hill):
C8H10BF4N3
Número CAS:
59016-56-7
Peso molecular:
234.99
Beilstein:
5685616
Número MDL:
MFCD00011998
Código UNSPSC:
12352108
ID de substância PubChem:
24892528
NACRES:
NA.32

Nível de qualidade

300

Formulário

powder

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[F-].FB(F)F.CN(C)c1cc[n+](cc1)C#N

InChI

1S/C8H10N3.BF3.FH/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3)4;/h3-6H,1-2H3;;1H/q+1;;/p-1

chave InChI

ONCRRSYBEJHQMM-UHFFFAOYSA-M

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Descrição geral

1-Cyano-4-dimethylaminopyridinium tetrafluoroborate is an organic cyanylating agent also termed CDAP. It is a unique cystine-labeling reagent due to its reactive nature under acidic conditions. This feature provides CDAP an advantage over other sulfhydryl labeling agents, as it can avoid potential thiol-disulfide exchange.

Aplicação

1-Cyano-4-dimethylaminopyridinium (CDAP) has been used in the synthesis of conjugate vaccines as a cyanylating agent. Activation of cellulose dialysis membrane for immunosensor applications used CDAP as an activation agent.

Características e benefícios

When compared to Cyanogen Bromide (CNBr), a similar reagent, CDAP is:

  • Easier to use.
  • Can operate at lower pH levels.
  • Fewer side reactions.
  • Cyanogen Bromide is hazardous in nature.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
0000223889
0000050872
0000087080
029M4177V
077M4106V

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