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C2470

Sigma-Aldrich

Coenzyme Q4

≥90%

Sinônimo(s):

2,3-Dimethoxy-5-methyl-6-(geranylgeranyl)-1,4-benzoquinone, Q-4, Ubiquinone-20, Ubiquinone-4

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About This Item

Fórmula empírica (Notação de Hill):
C29H42O4
Número CAS:
4370-62-1
Peso molecular:
454.64
Beilstein:
2066531
Número MDL:
MFCD00077923
Código UNSPSC:
12352204
ID de substância PubChem:
24892492
NACRES:
NA.51

Ensaio

≥90%

Formulário

liquid

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

COC1C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C)=C(C)C1=O

InChI

1S/C29H44O4/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-17-23(5)18-19-25-24(6)26(30)28(32-7)29(33-8)27(25)31/h12,14,16,18,28-29H,9-11,13,15,17,19H2,1-8H3/b21-14+,22-16+,23-18+

chave InChI

MDLQEORKYVBTDV-INVBOZNNSA-N

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Aplicação

Coenzyme Q4 (CoQ4) is a 4 isoprenyl group member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ4 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution.

Ações bioquímicas/fisiológicas

Increases the fluorescence polarization of perylene incorporated into ubiquinone-depleted mitochondrial and bilayer vesicles prepared from mitochondrial phospholipids

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BGBB8957
112M3908V
112M3908
089K3780
019K3781

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Coenzyme Q10-d9 (dimethoxy-d6, methyl-d3) ≥98 atom % D, ≥97% (CP)

Sigma-Aldrich

802891

Coenzyme Q10-d9 (dimethoxy-d6, methyl-d3)

Coenzyme Q10 solution 1 mg/mL in ethanol, certified reference material, ampule of 1 mL, Cerilliant®

Supelco

V-060

Coenzyme Q10 solution

Methyl-p-benzoquinone 98%

Sigma-Aldrich

211311

Methyl-p-benzoquinone

Duroquinone 97%

Sigma-Aldrich

D223204

Duroquinone

Menaquinone (K2) analytical standard

Supelco

47774

Menaquinone (K2)

Geranylgeranyl pyrophosphate ammonium salt solution, ≥95% (TLC), ~1 mg/mL in methanol: NH4OH (7:3)

Sigma-Aldrich

G6025

Geranylgeranyl pyrophosphate ammonium salt

p-Benzoquinona reagent grade, ≥98%

Sigma-Aldrich

B10358

p-Benzoquinona

Jolanta Dłużewska et al.
PloS one, 11(7), e0159629-e0159629 (2016-07-28)
In the present studies, we focused on substrate specificity of tocopherol cyclase, the key enzyme in the biosynthesis of the tocopherols and plastochromanol-8, the main plant lipid antioxidants, with special emphasis on the preference for tocopherols and plastochromanol-8 precursors, taking
T Kishi et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(12), 4653-4656 (1976-12-01)
Adriamycin inhibits the succinoxidase system and the NADH-oxidase system. Both of the intact mitocondrial enzymes and the pentane-extracted preparations are inhibited. The inhibition can be prevented by a molar ratio of coenzyme to adriamycin of 3:1 for coenzyme Q10 (ubiquinone)
V E Kagan et al.
Free radical biology & medicine, 9(2), 117-126 (1990-01-01)
Ubiquinones (CoQn) are intrinsic lipid components of many membranes. Besides their role in electron-transfer reactions they may act as free radical scavengers, yet their antioxidant function has received relatively little study. The efficiency of ubiquinols of varying isoprenoid chain length
Italo José B Durval et al.
Marine pollution bulletin, 157, 111357-111357 (2020-07-14)
In this study, Bacillus cereus was cultivated in a mineral medium composed of 2% frying oil and 0.12% peptone to produce a biosurfactant. The production was scaled up from flasks to 1.2-, 3.0- and 50-L bioreactors, where surface tension achieved
Jennifer Grant et al.
Disease models & mechanisms, 3(11-12), 799-806 (2010-10-05)
Coenzyme Q (CoQ) or ubiquinone is a lipid component of the electron transport chain required for ATP generation in mitochondria. Mutations in CoQ biosynthetic genes are associated with rare but severe infantile multisystemic diseases. CoQ itself is a popular over-the-counter
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