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Documentos Principais

A8412

Sigma-Aldrich

Albumina sérica bovina

7.5% in DPBS, sterile-filtered, BioXtra, suitable for cell culture

Sinônimo(s):

Albumina, Solução de BSA

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.75

fonte biológica

bovine

descrição

low endotoxin

esterilidade

sterile-filtered

linha de produto

BioXtra

Ensaio

7.0-8.0% protein basis (UV)

Formulário

liquid

peso molecular

66.4 kDa

purificado por

cold ethanol and heatshock fractionation

origem

USA origin

concentração

7.5% in DPBS

técnica(s)

cell culture | mammalian: suitable

Impurezas

≤13.0 EU/mL Endotoxin level

pH

6.5-7.5

atividade externa

Mycoplasma test (Negative)
cell growth >50%

Condições de expedição

ambient

temperatura de armazenamento

2-8°C

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Descrição geral

BSA is a single polypeptide chain consisting of about 583 amino acid residues and no carbohydrates. At pH 5-7 it contains 17 intrachain disulfide bridges and 1 sulfhydryl group.

Aplicação

Qualified for use in cell culture applications.

Ações bioquímicas/fisiológicas

Bovine serum albumin is broadly used as an additive to cell culture media, especially serum-free media (SFM). It provides a range of benefits including protection from oxidative damage and stabilization of other media components such as fatty acids and pyridoxal.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Journal of medicinal chemistry, 61(7), 3193-3208 (2018-03-15)
Isomers of chiral drugs can exhibit marked differences in biological activities. We studied the binding and inhibitory activities of 12 compounds against KDM5A. Among them are two pairs of enantiomers representing two distinct inhibitor chemotypes, namely, ( R)- and (
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Breast cancer research and treatment, 155(1), 37-52 (2015-12-15)
Despite the prevalence and significant morbidity resulting from estrogen receptor positive (ER(+)) breast adenocarcinomas, there are only a few models of this cancer subtype available for drug development and arguably none for studying etiology. Those models that do exist have
Amanda J Shapiro et al.
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The seroprevalence of Coxiella burnetii (C. burnetii) in cats in eastern Australia is unknown, and the risk of transmission from cats to humans is undetermined. This study aimed to determine the exposure of cats to C. burnetii in four distinct
Paul J Orchard et al.
Scientific reports, 9(1), 7858-7858 (2019-05-28)
Cerebral adrenoleukodystrophy (cALD) is an inflammatory neurodegenerative disease associated with mutation of the ABCD1 gene. Proteomic analysis of cerebral spinal fluid (CSF) from young males with active cALD revealed markers of inflammation including APOE4. APOE4 genotype has been associated with

Artigos

This page segues to comprehensive insights on how serum albumin and other important cell culture components affect the performance of serum-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of albumin. These insights may also be applied to ex vivo and tissue engineering applications.

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