75351

Oligomycin A

≥99% (HPLC)

• Sinônimo(s): MCH 32
• Fórmula empírica (Notação de Hill): C₄₅H₇₄O₁₁
• Número CAS: 579-13-5
• Peso molecular: 791.06
• Beilstein: 5702132
• Número CE: 209-437-3
• Número MDL: MFCD00065705
• Código UNSPSC: 51102829
• ID de substância PubChem: 57652563
• NACRES: NA.76

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥99% (HPLC)
• Formulário: powder
• cor: white to off-white
• solubilidade: DMSO: soluble
• espectro de atividade do antibiótico: fungi
• Modo de ação: enzyme | inhibits
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CCC1CCC2OC3(CC[C@@H](C)C(C[C@H](C)O)O3)[C@H](C)C(OC(=O)\C=C\[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C\1)[C@H]2C
• InChI: 1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15+,21-18+/t25-,26-,27+,28+,29+,30-,31+,32+,33-,34?,35?,36?,38+,40-,41?,42-,44+,45?/m1/s1
• chave InChI: MNULEGDCPYONBU-VVXVDZGXSA-N

Descrição

Descrição geral

Chemical structure: macrolide

Aplicação

Oligomycin was used to inhibit sucrose synthesis and ¹⁴C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O₂ and CO₂ in the cat. Inhibits the growth of Rhodotorula glutinis, Aspergillus niger and other molds.

Ações bioquímicas/fisiológicas

Oligomycin blocks oxidative phosphorylation and the electron transport chain by inhibiting membrane bound mitochondrial ATP synthase (ATPase) and proton channel (pump, FO subunit) blocker.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves