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495455

Sigma-Aldrich

Oligomycin

≥90% (mixture of A, B, and C isomers, HPLC), powder, Antibiotic, Calbiochem

Sinônimo(s):

Oligomycin

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About This Item

Fórmula empírica (Notação de Hill):
C45H74O11
Número CAS:
1404-19-9
Peso molecular:
791.06
Número MDL:
MFCD01779388
Código UNSPSC:
12352200
NACRES:
NA.77

Nome do produto

Oligomycin, A mixture of A, B, and C isomers.

Nível de qualidade

100

Ensaio

≥90% (mixture of A, B, and C isomers, HPLC)

Formulário

powder

fabricante/nome comercial

Calbiochem®

condição de armazenamento

OK to freeze

cor

white

Condições de expedição

ambient

temperatura de armazenamento

−20°C

InChI

1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+

chave InChI

MNULEGDCPYONBU-ZUSSGZTJSA-N

Descrição geral

A mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.

Ações bioquímicas/fisiológicas

Cell permeable: no
Primary Target
Membrane-bound mitochondrial ATPase (F1)
Product does not compete with ATP.
Reversible: no

Advertência

Toxicity: Irritant (B)

Reconstituição

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.

Outras notas

Wolvetang, E.J., et al. 1994. FEBS Lett.339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther.264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett.315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta1141, 231.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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