42602

Propionyl-L-carnitine

≥94.0% (HPLC), suitable for LC/MS

• Sinônimo(s): (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine
• Fórmula empírica (Notação de Hill): C₁₀H₁₉NO₄
• Número CAS: 20064-19-1
• Peso molecular: 217.26
• Número MDL: MFCD00870024
• Código UNSPSC: 12352209
• ID de substância PubChem: 329756246
• NACRES: NA.26

Propriedades

• product name: Propionyl-L-carnitine, ≥94.0% (HPLC)
• Nível de qualidade: 100
• Ensaio: ≥94.0% (HPLC)
• forma: powder or crystals
• atividade óptica: [α]/D -23±3°, c = 1 in H₂O
• técnica(s): LC/MS: suitable
• Impurezas: ≤10% water (calcd. from elemental analysis)
• cor: white to off-white
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
• InChI: 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
• chave InChI: UFAHZIUFPNSHSL-MRVPVSSYSA-N

Descrição

Descrição geral

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

Aplicação

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Ações bioquímicas/fisiológicas

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable