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42623

Sigma-Aldrich

Butyryl-L-carnitine

≥97.0% (TLC)

Sinônimo(s):

(2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxobutoxy)-1-propanaminium inner salt, Butanoyl-L-carnitine, C4-Carnitine

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About This Item

Fórmula empírica (Notação de Hill):
C11H21NO4
Número CAS:
25576-40-3
Peso molecular:
231.29
Número MDL:
MFCD01674827
Código UNSPSC:
12352200
ID de substância PubChem:
329756249
NACRES:
NA.26

Nível de qualidade

100

Ensaio

≥97.0% (TLC)

forma

powder, crystals or chunks

atividade óptica

[α]/D -23±2°, c = 1 in H2O

cor

white to off-white

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

C[N+](C)(C)C[C@H](OC(CCC)=O)CC([O-])=O

InChI

1S/C11H21NO4/c1-5-6-11(15)16-9(7-10(13)14)8-12(2,3)4/h9H,5-8H2,1-4H3/t9-/m1/s1

chave InChI

QWYFHHGCZUCMBN-SECBINFHSA-N

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Categorias relacionadas

Aplicação


  • Lead exposure induces metabolic reprogramming in rat models.: This study by Mani MS et al. investigates the metabolic effects of lead exposure in rat models, focusing on the biochemical pathways affected. The research highlights the role of butyryl-ʟ-carnitine in counteracting lead-induced metabolic disruptions, suggesting its potential therapeutic applications in mitigating heavy metal toxicity (Mani et al., 2020).

Ações bioquímicas/fisiológicas

Butyrylcarnitine is elevated in patients with Acyl-CoA dehydrogenase, short-chain (SCAD) deficiency, in infants with acute acidosis and generalized muscle weakness and in middle-aged patients with chronic myopathy localized in muscle; very long chain Acyl-CoA dehydrogenase deficiency, and celiac disease.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Myristoyl-L-carnitine ≥97.0% (HPLC)

Sigma-Aldrich

61367

Myristoyl-L-carnitine

Glutaryl-L-carnitine lithium salt ≥98.0% (TLC)

Sigma-Aldrich

72715

Glutaryl-L-carnitine lithium salt

Propionyl-L-carnitine-(N-methyl-d3) analytical standard

Supelco

52941

Propionyl-L-carnitine-(N-methyl-d3)

Propionyl-L-carnitine analytical standard

Supelco

91275

Propionyl-L-carnitine

Valeryl-L-carnitine analytical standard

Supelco

04265

Valeryl-L-carnitine

O-Acetyl-L-carnitine hydrochloride ≥99% (titration), powder

Sigma-Aldrich

A6706

O-Acetyl-L-carnitine hydrochloride

Stearoyl-L-carnitine ≥97.0% (TLC)

Sigma-Aldrich

61229

Stearoyl-L-carnitine

Tigloyl-L-carnitine analytical standard

Supelco

39588

Tigloyl-L-carnitine

3-Hydroxyisovaleryl-L-carnitine analytical standard

Supelco

91298

3-Hydroxyisovaleryl-L-carnitine

Palmitoyl-L-carnitine ≥97.0% (HPLC)

Sigma-Aldrich

61251

Palmitoyl-L-carnitine

R Golan et al.
International journal of andrology, 6(4), 349-357 (1983-08-01)
Bioautography of human semen demonstrated the presence of L-carnitine, acetylcarnitine, propionylcarnitine and C4-acylcarnitines (butyrylcarnitines). In studies designed to ascertain the organs secreting these compounds into semen it was found that: Quantitative analyses of semen obtained pre- and post-vasectomy showed markedly
Sarah P Young et al.
Clinica chimica acta; international journal of clinical chemistry, 337(1-2), 103-113 (2003-10-22)
Homozygosity and compound heterozygosity for the short chain acyl-CoA dehydrogenase (SCAD) gene sequence variants 625G-->A and 511C-->T are associated with ethylmalonic aciduria (EMA), a biochemical indicator of SCAD deficiency. The clinical and biochemical implications of these variants are not fully
S Benito et al.
The Analyst, 143(18), 4448-4458 (2018-08-29)
Pediatric chronic kidney disease (CKD) is a clinical syndrome characterized by renal hypofunction occurring due to gradual and irreversible kidney damage that can further progress over time. New biomarkers may help early diagnosis of pediatric patients suffering from CKD and
A Bhala et al.
The Journal of pediatrics, 126(6), 910-915 (1995-06-01)
We identified two additional patients with short-chain acyl-coenzyme A (CoA), further characterized the clinical and biochemical features of this defect, and compared it with other fatty acid oxidation defects. We have measured the in vitro short-chain acyl-coenzyme A dehydrogenase (SCAD)
Josiane Joseph et al.
Metabolites, 8(4) (2018-10-05)
Duchenne muscular dystrophy (DMD) is a musculoskeletal disorder that causes severe morbidity and reduced lifespan. Individuals with DMD have an X-linked mutation that impairs their ability to produce functional dystrophin protein in muscle. No cure exists for this disease and
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