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Documentos Principais

40941

Sigma-Aldrich

Methylphosphonic acid

99.0-101.0% (T)

Sinônimo(s):

MPA

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About This Item

Fórmula linear:
CH3P(O)(OH)2
Número CAS:
Peso molecular:
96.02
Beilstein:
1739372
Número CE:
Número MDL:
Código UNSPSC:
12352204
ID de substância PubChem:
NACRES:
NA.25

Nível de qualidade

Ensaio

99.0-101.0% (T)

perda

≤2.0% loss on drying

pH

0.9-1.4

pf

103-109 °C
105-107 °C (lit.)

solubilidade

H2O: 2.88 g in 30 mL, clear, colorless

traços de cátion

Al: ≤5 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

Absorção UV

λ: 260 nm Amax: ≤0.05
λ: 280 nm Amax: ≤0.04

cadeia de caracteres SMILES

CP(O)(O)=O

InChI

1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4)

chave InChI

YACKEPLHDIMKIO-UHFFFAOYSA-N

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Aplicação

Highly pure methylphosphonic acid for phosphoproteome analysis

Pictogramas

CorrosionExclamation mark

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

>392.0 °F - Pensky-Martens closed cup

Ponto de fulgor (°C)

> 200 °C - Pensky-Martens closed cup


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C E Pritchard et al.
Nucleic acids research, 22(13), 2592-2600 (1994-07-11)
The HIV-1 regulatory proteins tat and rev are both RNA binding proteins which recognize sequences in duplex RNA which are close to structural distortions. Here we identify phosphate contacts which are critical for each binding reaction by use of a
H Lindner et al.
Journal of chromatography. A, 782(1), 55-62 (1998-01-24)
A new two-step high-performance liquid chromatography (HPLC) procedure has been developed to separate modified histone H1 subtypes. Reversed-phase (RP) HPLC followed by hydrophilic-interaction liquid chromatography (HILIC) was used for analytical and semi-preparative scale fractionation of multi-phosphorylated H1 histone subtypes into
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Journal of proteome research, 11(8), 4269-4276 (2012-07-10)
In large-scale phosphoproteomics studies, fractionation by strong cation exchange (SCX) or electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) is commonly used to reduce sample complexity, fractionate phosphopeptides from their unmodified counterparts, and increase the dynamic range for phosphopeptide identification. However, these procedures
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Journal of proteome research, 10(8), 3474-3483 (2011-06-21)
Reversible phosphorylations play a critical role in most biological pathways. Hence, in signaling studies great effort has been put into identification of a maximum number of phosphosites per experiment. Mass spectrometry (MS)-based phosphoproteomics approaches have been proven to be an
Stefan Loroch et al.
Analytical chemistry, 87(3), 1596-1604 (2014-11-19)
In the past decade, several strategies for comprehensive phosphoproteome analysis have been introduced. Most of them combine different phosphopeptide enrichment techniques and require starting material in the milligram range, as a consequence of their insufficient sensitivity. This limitation impairs the

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