31389
Dextran
Mr ~40,000
Sinônimo(s):
DEXTRAN 40
About This Item
Produtos recomendados
fonte biológica
(Leuconostoc spp)
Nível de qualidade
Formulário
powder
peso molecular
Mr ~40,000
técnica(s)
cryopreservation: suitable
gel permeation chromatography (GPC): suitable
perda
≤7% loss on drying
cor
white
pf
483 °C ((901 °F ))
solubilidade
water: 1.5, clear, colorless
Absorção
≤0.05 at 375 nm in H2O at 10%
adequação
suitable for additive or modifier in the separation of proteins or peptides
aplicação(ões)
advanced drug delivery
agriculture
sample preparation
temperatura de armazenamento
room temp
cadeia de caracteres SMILES
O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O
InChI
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
chave InChI
FZWBNHMXJMCXLU-UHFFFAOYSA-N
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Descrição geral
Aplicação
- to mix with embryo suspension in seawater to prepare the sample for cryo-imaging
- to immerse the tails of zebrafish larvae for cryoimmobilization
- in the synthesis of vinyl sulfone modified dextran (DX-VS)
- in the synthesis of methacrylate functionalized dextran via ester linkage (DX-O-MeA)
- as a supplement in NCTC-135 tissue culture medium to prepare the perfusion medium
Dextran 40 is used in the development of new improved preservation solutions for organ transplantation. Dextran 40 may be used to determine cell tightness and flux parameters across cell layers. Dextran 40 is used as a colloidal plasma volume extender.
Ações bioquímicas/fisiológicas
-Cryoprotection: Dextran acts as a cryoprotectant by forming a protective barrier around cells and tissues during freezing. This barrier inhibits the formation of ice crystals, which can damage cell membranes and structures.
-Viscosity Control: Dextran can alter the viscosity of solutions by increasing the molecular weight of the solution. This change in viscosity affects the flow properties of the solution, making it useful for controlling the thickness of solutions in various processes.
-Drug Delivery: Modified dextran serves as a carrier for controlled drug delivery. Dextran can encapsulate drugs and release them gradually, enhancing drug solubility and controlling the release profiles to improve therapeutic outcomes.
-Gel Electrophoresis: Dextran increases the density of sample loading solutions in gel electrophoresis. This increased density helps samples sink into the gel matrix, allowing for more precise separation of molecules based on size and charge during electrophoresis.
-Enzyme Stabilization: Dextran stabilizes enzymes by providing a protective environment. It forms a stable matrix around enzymes, enhancing their activity and extending their lifespan in various biochemical reactions. This protection prevents enzyme denaturation and inactivation, allowing enzymes to function more effectively.
Características e benefícios
- Dextran with an average molecular weight of 40,000
- Freely soluble in Water, DMSO, formamide, ethylene glycol, and glycerol
- Versatile and adaptable for various laboratory and research applications
Outras notas
produto comparável
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 2
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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