P4722

Piridoxina

meets USP testing specifications

• Sinônimo(s): Adermina, HCl PN, Piridoxol, Vitamina B₆
• Fórmula empírica (Notação de Hill): C₈H₁₁NO₃ · HCl
• Número CAS: 58-56-0
• Peso molecular: 205.64
• Beilstein: 3632435
• Número CE: 200-386-2
• Número MDL: MFCD00012807
• Código UNSPSC: 12352205
• eCl@ss: 34058008
• ID de substância PubChem: 24898493
• NACRES: NA.21

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 200
• Agency: USP/NF; meets USP testing specifications
• Ensaio: 98.0-102.0% dry basis
• forma: powder
• cor: white
• pf: 214-215 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• cadeia de caracteres SMILES: Cl[H].Cc1ncc(CO)c(CO)c1O
• InChI: 1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
• chave InChI: ZUFQODAHGAHPFQ-UHFFFAOYSA-N

Descrição

Descrição geral

Vitamin B group is water-soluble and exists in six forms namely the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. The food sources of vitamin B₆ include grains, nuts, fruits, vegetables and meat.

Aplicação

Pyridoxine hydrochloride has been used to test its neuroprotective functionality in traumatic brain injury (TBI) rats. It has also been used as a reference standard to quantify vitamin B₆ in feed and digesta samples using high-performance liquid chromatography(HPLC).

Ações bioquímicas/fisiológicas

Pyridoxine plays a key role in metabolism both carbohydrates and amino acids. It supports brain development and its deficiency levels may lead to depletion of γ-aminobutyric acid (GABA) levels. Pyridoxine catalyzes the neurotransmitter biosynthesis like dopamine and serotonin. Pyridoxine in excess or deficient may lead to neuropathy.

Informações de segurança

• Pictogramas: GHS05
• Palavra indicadora: Danger
• Frases de perigo: H318
• Declarações de precaução: P280 - P305 + P351 + P338
• Classificações de perigo: Eye Dam. 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)