C8731

Calcium pantothenate

meets USP testing specifications, monograph mol wt. 476.53 (C₁₈H₃₂CaN₂O₁₀)

• Sinônimo(s): D-Pantothenic acid hemicalcium salt, (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, Calcium D-pantothenate, Vitamin B₅
• Fórmula linear: HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
• Número CAS: 137-08-6
• Peso molecular: 238.27
• Beilstein: 3769272
• Número CE: 205-278-9
• Número MDL: MFCD00002766
• Código UNSPSC: 12352205
• eCl@ss: 34058012
• ID de substância PubChem: 24893098
• NACRES: NA.21

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 200
• Agency: USP/NF; meets USP testing specifications
• Formulário: crystalline; powder
• peso molecular: monograph mol wt. 476.53 (C₁₈H₃₂CaN₂O₁₀)
• técnica(s): cell culture | mammalian: suitable; cell culture | plant: suitable
• cor: white
• aplicação(ões): pharmaceutical (small molecule)
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
• InChI: 1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
• chave InChI: FAPWYRCQGJNNSJ-UBKPKTQASA-L

Descrição

Descrição geral

Vitamin B5 or pantothenic acid is a viscous oil that is soluble in ethanol and water. It is produced by plants and microorganisms. d-(+)pantothenic acid is the naturally occurring form of pantothenic acid and is biologically active.

Aplicação

Calcium pantothenate has been used:

• as a component of vitamin solution for synthetic media
• as a component of vitamin mix for the ICS medium mix
• as a component of a chemically defined diet for metal depletion studies in Drosophila
• as a supplement to study coenzyme A metabolism in mouse models of non-alcoholic steatohepatitis

Precursor in the biosynthesis of coenzyme A.

Ações bioquímicas/fisiológicas

The calcium salts of panthenol are commonly used for pharmaceutical preparations. Pantothenate is a component of coenzyme A and is useful in its synthesis. Pantothenic acid is also involved in the synthesis of heme, cholesterol and fatty acids. Since vitamin B5 is found in all foods, its deficiency is not commonly observed.

propriedades físicas

Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)