P5155

D-Pantothenic acid hemicalcium salt

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

• Sinônimo(s): (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, Calcium D-pantothenate, Vitamin B₅
• Fórmula linear: HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
• Número CAS: 137-08-6
• Peso molecular: 238.27
• Beilstein: 3769272
• Número CE: 205-278-9
• Número MDL: MFCD00002766
• Código UNSPSC: 12352205
• eCl@ss: 34058012
• ID de substância PubChem: 24898601
• NACRES: NA.75

Propriedades

• fonte biológica: synthetic (organic)
• linha de produto: BioReagent
• Ensaio: ≥98% (TLC)
• forma: powder
• peso molecular: M_w 238.27 g/mol
• técnica(s): cell culture | insect: suitable; cell culture | mammalian: suitable; cell culture | plant: suitable
• cor: white to off-white
• pH: 7.0-8 (25 °C, 50 g/L)
• solubilidade: water: soluble 50 mg/mL, clear, colorless
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
• InChI: 1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
• chave InChI: FAPWYRCQGJNNSJ-UBKPKTQASA-L

Descrição

Descrição geral

Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid. It is water soluble and quite stable to heating.

Aplicação

D-Pantothenic acid hemicalcium salt has been used:

• as a component of FMX-turbodoma- derived media
• as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation
• as a supplement in preadipocyte media

Precursor in the biosynthesis of coenzyme A.

Ações bioquímicas/fisiológicas

Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein. These are essential cofactors involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.

propriedades físicas

Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)