BP1094

Cyclophosphamide

British Pharmacopoeia (BP) Reference Standard

• Sinônimo(s): Cyclophosphamide monohydrate, 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan
• Fórmula empírica (Notação de Hill): C₇H₁₅Cl₂N₂O₂P · H₂O
• Número CAS: 6055-19-2
• Peso molecular: 279.10
• Beilstein: 4678992
• Número MDL: MFCD00149395
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: cyclophosphamide
• forma: crystalline
• prazo de validade: limited shelf life, expiry date on the label
• fabricante/nome comercial: BP
• pf: 49-51 °C (lit.)
• aplicação(ões): pharmaceutical; pharmaceutical small molecule
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• chave InChI: PWOQRKCAHTVFLB-UHFFFAOYSA-N

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Cyclophosphamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Cyclophosphamide Oral Solution

Ações bioquímicas/fisiológicas

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Embalagem

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H301,H340,H350,H360FD
• Declarações de precaução: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Classificações de perigo: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 235.4 °F - closed cup
• Ponto de fulgor (°C): 113 °C - closed cup