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C3250000

Cyclophosphamide

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

Cyclophosphamide monohydrate, 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan

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About This Item

Fórmula empírica (Notação de Hill):
C7H15Cl2N2O2P · H2O
Número CAS:
6055-19-2
Peso molecular:
279.10
Beilstein:
4678992
Número MDL:
MFCD00149395
Código UNSPSC:
41116107
ID de substância PubChem:
329775031
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

cyclophosphamide

fabricante/nome comercial

EDQM

pf

49-51 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

chave InChI

PWOQRKCAHTVFLB-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Cyclophosphamide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Ações bioquímicas/fisiológicas

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Frases de perigo

H301,H340,H350,H360FD

Classificações de perigo

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

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Certificados de análise (COA)

Lot/Batch Number

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Sigma-Aldrich

F6627

5-Fluorouracil

Doxorrubicina 98.0-102.0% (HPLC)

Sigma-Aldrich

D1515

Doxorrubicina

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