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91209

Supelco

Carnosic acid

analytical standard

Sinônimo(s):

(4aR,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-phenanthrene-4a-carboxylic acid, Salvin

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About This Item

Fórmula empírica (Notação de Hill):
C20H28O4
Número CAS:
Peso molecular:
332.43
Beilstein:
2707918
Número MDL:
Código UNSPSC:
85151701
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

Ensaio

≥95.0% (HPLC)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

Impurezas

≤5.0% water

aplicação(ões)

food and beverages

Formato

neat

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C(O)=O)c2c(O)c1O

InChI

1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1

chave InChI

QRYRORQUOLYVBU-VBKZILBWSA-N

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Descrição geral

Carnosic acid is a polyphenolic diterpene, which can be obtained from rosemary. It may possess various pharmacological properties like antioxidant, anticancer and also antimutagenic property.

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

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Carnosic acid inhibits proliferation and augments differentiation of human leukemic cells induced by 1, 25-dihydroxyvitamin dsub3 and retinoic acid
Steiner M, et al.
Nutrition and Cancer, 41, 135-144 (2001)
Michael Danilenko et al.
Experimental cell research, 298(2), 339-358 (2004-07-22)
Differentiation therapy holds promise as an alternative to cytotoxic drug therapy of cancer. Among compounds under scrutiny for this purpose is the physiologically active form of vitamin D(3), 1,25-dihydroxyvitamin D(3), and its chemically modified derivatives. However, the propensity of vitamin
Margarita González-Vallinas et al.
PloS one, 9(6), e98556-e98556 (2014-06-04)
Colorectal and pancreatic cancers remain important contributors to cancer mortality burden and, therefore, new therapeutic approaches are urgently needed. Rosemary (Rosmarinus officinalis L.) extracts and its components have been reported as natural potent antiproliferative agents against cancer cells. However, to
María Romo-Vaquero et al.
PloS one, 9(4), e94687-e94687 (2014-04-16)
Carnosic acid (CA) and rosemary extracts (RE) show body-weight, energy metabolism and inflammation regulatory properties in animal models but the mechanisms are not yet understood. Gut microbiota plays an important role in the host metabolism and inflammatory status and is
Leila Maringer et al.
Electrophoresis, 36(2), 348-354 (2014-10-14)
The combination of CE and MS is now a widely used tool that can provide a combination of high resolution separations with detailed structural information. Recently, we highlighted the benefits of an approach to add further functionality to this well-established

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