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00390580

Rosmarinic acid

primary reference standard

Sinônimo(s):

(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester

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About This Item

Fórmula empírica (Notação de Hill):
C18H16O8
Número CAS:
20283-92-5
Peso molecular:
360.31
Beilstein:
2227587
Número MDL:
MFCD00017740
Código UNSPSC:
85151701
ID de substância PubChem:
329747058
NACRES:
NA.24

grau

primary reference standard

prazo de validade

limited shelf life, expiry date on the label

fabricante/nome comercial

HWI

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

171-175 °C (lit.)

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2

InChI

1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1

chave InChI

DOUMFZQKYFQNTF-WUTVXBCWSA-N

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Descrição geral

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Aplicação

Reference standard in the analysis of herbal medicinal products.

Ações bioquímicas/fisiológicas

Rosmarinic acid has shown to contain antioxidant and anti-inflammatory activities. Possesses promising physiological actions related to cognitive performance, Alzheimer′s disease prevention, kidney disease treatment, cardioprotection and cancer chemoprevention.

Outras notas

This compound is commonly found in plants of the genus: melissa mentha salvia thymus

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
HWI02735-1
HWI02133-1
HWI00981
HWI00131-4
HWI00131-3

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Robert Domitrović et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 51, 370-378 (2012-11-03)
The aim of this study was to investigate the therapeutic potential of rosmarinic acid (RA), a natural phenolic, in the treatment of acute liver toxicity. RA at 10, 25 and 50mg/kg was administered by gavage once daily for 2 consecutive
Anja Klančnik et al.
PloS one, 7(12), e51800-e51800 (2013-01-04)
Campylobacter is a major foodborne pathogen and alternative antimicrobials are needed to prevent or decrease Campylobacter contamination in foods or food producing animals. The objectives of this study are to define the anti-Campylobacter activities of natural phenolic compounds of plant
Cristina Airoldi et al.
Chemistry, an Asian journal, 8(3), 596-602 (2013-01-11)
Amyloid peptides, Aβ1-40 and Aβ1-42, represent major molecular targets to develop potential drugs and diagnostic tools for Alzheimer's Disease (AD). In fact, oligomeric and fibrillar aggregates generated by these peptides are amongst the principal components of amyloid plaques found post
Rodrigo Lucarini et al.
Pharmaceutical biology, 51(9), 1087-1090 (2013-06-07)
Despite several pharmacological applications of Rosmarinus officinalis L. (Lamiaceae), studies on its analgesic and anti-inflammatory properties have been scarce. The aim of this work was to use in vivo models to evaluate the analgesic and anti-inflammatory activities of the aqueous
Juan A Martín et al.
PloS one, 8(2), e56987-e56987 (2013-03-08)
Efforts to introduce pathogen resistance into landscape tree species by breeding may have unintended consequences for fungal diversity. To address this issue, we compared the frequency and diversity of endophytic fungi and defensive phenolic metabolites in elm (Ulmus spp.) trees
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