49702

Carnosol

analytical standard

• Sinônimo(s): Picrosalvin
• Fórmula empírica (Notação de Hill): C₂₀H₂₆O₄
• Número CAS: 5957-80-2
• Peso molecular: 330.42
• Número MDL: MFCD02752467
• Código UNSPSC: 85151701
• ID de substância PubChem: 329757507
• NACRES: NA.24

Propriedades

• fonte biológica: Rosemarinus officinalis L. leaves
• Nível de qualidade: 100
• grau: analytical standard
• Ensaio: ≥98.0% (HPLC)
• prazo de validade: limited shelf life, expiry date on the label
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): food and beverages
• Formato: neat
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O
• InChI: 1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1
• chave InChI: XUSYGBPHQBWGAD-PJSUUKDQSA-N

Descrição

Descrição geral

Carnosol is a naturally occurring phyto polyphenolor phenolic diterpene, found in rosemary, which can show a broad spectrum of applications as a an antioxidant, anticancer agent and anti-inflammatory agent.

Carnosol is one of the phenolic antioxidants present in extracts of the herb rosemary (Rosmarinus officinalis). Carnosol inhibits the formation of tumors derived using irritants such as TPA and DMBA in murine models of carcinogenesis.The effective dose reported is 1-10 μM topically or 6 μg/ml when added to supernatants of cultured cells.Addition of rosemary extracts to the diet as a 1% supplement by weight was also found to decrease the frequency of DMBA-DNA adducts.

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ações bioquímicas/fisiológicas

A phenolic diterpene with antioxidant and anticarcinogenic activities.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Outras notas

This compound is commonly found in plants of the genus: salvia

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P280 - P302 + P352
• Classificações de perigo: Skin Sens. 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable