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Key Documents

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35394

Supelco

Albendazole sulfone

VETRANAL®, analytical standard

Sinônimo(s):

Methyl [5-(propylsulfonyl)-1H-benzimidazol-2-yl]carbamate

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About This Item

Fórmula empírica (Notação de Hill):
C12H15N3O4S
Número CAS:
75184-71-3
Peso molecular:
297.33
Beilstein:
8394880
Número MDL:
MFCD00600775
Código UNSPSC:
41116107
ID de substância PubChem:
329755154
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

linha de produto

VETRANAL®

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

forensics and toxicology
pharmaceutical (small molecule)

formato

neat

cadeia de caracteres SMILES

CCCS(=O)(=O)c1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O4S/c1-3-6-20(17,18)8-4-5-9-10(7-8)14-11(13-9)15-12(16)19-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

chave InChI

CLSJYOLYMZNKJB-UHFFFAOYSA-N

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Descrição geral

Albendazole sulfone is a nonactive metabolite of albendazole sulfoxide (ABZSO).

Aplicação

Albendazole sulfone may be used as a reference standard in the determination of albendazole sulfone in plasma samples using high-performance liquid chromatography (HPLC) technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações legais

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palavra indicadora

Warning

Frases de perigo

H361d,H373,H410

Classificações de perigo

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

Órgãos-alvo

Adrenal gland,spleen,male reproductive organs,Blood

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCH9379
BCCF2328
BCCC6525
BCCB7892
BCBZ5671

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Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

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Victoria Miró et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(4), 408-414 (2019-07-16)
Combinations of bioactive phytochemicals with synthetic compounds have been suggested as promissory tools for the improvement of nematode control in livestock. Bioactive phytochemicals may interfere with the activity of drug-metabolizing enzymes and delay the metabolic conversion of anthelmintics into less
Constant Edi et al.
PLoS neglected tropical diseases, 13(5), e0007325-e0007325 (2019-05-21)
A single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used for mass drug administration programs for
Zenaís Busatto et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(4), 509-519 (2016-12-17)
This paper describes the development of analytical methods for the quantification of albendazole (ABZ) in fish feed and ABZ and its main known metabolites (albendazole sulfoxide, albendazole sulfone and albendazole aminosulfone) in fish fillet employing LC-MS/MS. In order to assess
Simultaneous determination of albendazole sulfoxide enantiomers and albendazole sulfone in plasma.
Lanchote LV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 709(2), 273-279 (1998)
Noemi Cowan et al.
International journal for parasitology. Drugs and drug resistance, 7(2), 159-173 (2017-04-04)
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug uptake into gastrointestinal nematodes responsible for the pharmacological effect are unknown. We assessed
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