12666

Albumin, Human Serum, Fraction V, Low Heavy Metals

• Sinônimo(s): Albumin, Human Serum, Fraction V, Low Heavy Metals
• Número CAS: 70024-90-7
• Número MDL: MFCD00081418
• Código UNSPSC: 12352202
• NACRES: NA.25

Propriedades

• descrição: Merck USA index - 14, 8468
• Ensaio: ≥95% (SDS-PAGE)
• Formulário: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze
• Impurezas: ≤5.0% Ash; ≤6% moisture
• pI: 4.7
• solubilidade: water: 50 mg/mL
• traços de cátion: heavy metals: ≤20 ppm
• Condições de expedição: ambient
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• chave InChI: QYSGYZVSCZSLHT-UHFFFAOYSA-N

Descrição

Descrição geral

Human serum albumin (HSA) is an abundant protein found in the plasma. This globular, soluble, and unglycosylated monomeric protein, has three homologous domains (I, II, and III). These domains have subdomains A and B having common structural motifs. The HSA gene is located on the human chromosome 4q13.3.

Aplicação

Albumin, Human Serum, Fraction V, Low Heavy Metals has been used:

• as a supplement in double buffer and milliQ-water for in vivo
• in serum-free media for polarized secretion assays in human dermal microvascular endothelial cells
• as a supplement in sodium phosphate buffer for the reconstitution of hormone lysis samples

Ações bioquímicas/fisiológicas

Human serum albumin (HSA) is very crucial in stabilizing extracellular fluid volume. It functions as an excipient for vaccines and therapeutic protein drugs. HSA serves as a cell culture medium supplement for the synthesis of vaccines and pharmaceuticals. It is useful as a carrier protein for steroids, fatty acids, and thyroid hormones. HSA is used to treat cardiopulmonary bypass, trauma, hemorrhage, and hypoalbuminemia. HSA is useful in biological applications, such as implantable biomaterials, biochromatography, surgical adhesives, and sealants.

Advertência

Toxicity: Standard Handling (A)

Nota de preparo

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstituição

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable