1.06666

Citrato de sódio tribásico

EMPROVE^® API Ph Eur,BP,JP,USP

• Sinônimo(s): Citrato trissódico, Ácido cítrico
• Fórmula linear: HOC(COONa)(CH₂COONa)₂ · 2H₂O
• Número CAS: 6132-04-3
• Peso molecular: 294.10
• Beilstein: 6104939
• Número MDL: MFCD00150031
• Código UNSPSC: 12352302
• Número do índice EC: 200-675-3

Propriedades

• Agency: BP; JP; Ph. Eur.; USP
• Nível de qualidade: 600
• linha de produto: EMPROVE^® API
• Formulário: solid
• potência: >8000 mg/kg LD₅₀, oral (Rat)
• pH: 7.5-9.0 (25 °C, 50 g/L in H₂O)
• pf: 150 °C (anhydrous substance); >300 °C (lit.)
• solubilidade: 720 g/L
• densidade volumétrica: 600 kg/m³
• aplicação(ões): liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical; solid formulation
• temperatura de armazenamento: 2-25°C
• cadeia de caracteres SMILES: O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
• InChI: 1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
• chave InChI: NLJMYIDDQXHKNR-UHFFFAOYSA-K

Descrição

Descrição geral

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicação

tri-Sodium citrate dihydrate is used as anticoagulant in dialysis and plasmapheresis. tri-Sodium citrate dihydrate Emprove^® API is manufactured according to ICH Q7 guidelines. An ASMF and US-DMF is available.

Informações legais

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable