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855775C

Avanti

18:0 Lyso PC

1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine, chloroform

Sinônimo(s):

1-octadecanoyl-sn-glycero-3-phosphocholine; PC(18:0/0:0)

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About This Item

Fórmula empírica (Notação de Hill):
C26H54NO7P
Número CAS:
19420-57-6
Peso molecular:
523.68
Número MDL:
MFCD00152125
Código UNSPSC:
51191904
NACRES:
NA.25

Ensaio

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

Formulário

liquid

embalagem

pkg of 1 × 2.5 mL (855775C-25mg)
pkg of 1 × 20 mL (855775C-500mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 855775C

concentração

10 mg/mL (855775C-25mg)
25 mg/mL (855775C-500mg)

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[P](=O)([O-])(OCC[N+](C)(C)C)OCC(O)COC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C26H54NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h25,28H,5-24H2,1-4H3

chave InChI

IHNKQIMGVNPMTC-UHFFFAOYSA-N

Aplicação

18:0 Lyso PC has been used in gametocytogenesis assay.

Embalagem

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (855775C-500mg)
5 mL Clear Glass Sealed Ampule (855775C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Órgãos-alvo

Central nervous system, Liver,Kidney

Classe de risco de água (WGK)

WGK 3

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Certificados de análise (COA)

Lot/Batch Number

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Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum
Brancucci NMB, et al.
Cell, 171(7), 1532-1544 (2017)
Anthony J Valente et al.
Free radical biology & medicine, 70, 117-128 (2014-02-25)
Oxidized low-density lipoprotein (oxLDL) induces endothelial cell death through the activation of NF-κB and AP-1 pathways. TRAF3IP2 is a redox-sensitive cytoplasmic adapter protein and an upstream regulator of IKK/NF-κB and JNK/AP-1. Here we show that oxLDL-induced death in human primary
Dumindika A Siriwardane et al.
International journal of pharmaceutics, 578, 119077-119077 (2020-01-29)
Identification and quantification of excipient related degradation products in the liposomal formulation is important, as they may impact the safety and efficacy of the drug. Phospholipids are one of the major excipients in liposome drugs composing the lipid bilayer, and
Otto K Kari et al.
Nanoscale, 12(3), 1728-1741 (2020-01-03)
Methodological constraints have limited our ability to study protein corona formation, slowing nanomedicine development and their successful translation into the clinic. We determined hard and soft corona structural properties along with the corresponding proteomic compositions on liposomes in a label-free
Danielle M Charron et al.
Langmuir : the ACS journal of surfaces and colloids, 36(19), 5385-5393 (2020-04-28)
Porphyrin aggregates have attractive photophysical properties for phototherapy and optical imaging, including quenched photosensitization, efficient photothermal conversion, and unique absorption spectra. Although hydrophobic porphyrin photosensitizers have long been encapsulated into liposomes for drug delivery, little is known about the membrane
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