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855575P

Avanti

14:0 Lyso PC

1-myristoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder

Sinônimo(s):

1-tetradecanoyl-sn-glycero-3-phosphocholine; PC(14:0/0:0)

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About This Item

Fórmula empírica (Notação de Hill):
C22H46NO7P
Número CAS:
20559-16-4
Peso molecular:
467.58
Código UNSPSC:
51191904
NACRES:
NA.25

Ensaio

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

forma

powder

embalagem

pkg of 1 × 1 g (855575P-1g)
pkg of 1 × 200 mg (855575P-200mg)
pkg of 1 × 25 mg (855575P-25mg)
pkg of 1 × 500 mg (855575P-500mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 855575P

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCC)=O

InChI

1S/C22H46NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-22(25)28-19-21(24)20-30-31(26,27)29-18-17-23(2,3)4/h21,24H,5-20H2,1-4H3/t21-/m1/s1

chave InChI

VXUOFDJKYGDUJI-OAQYLSRUSA-N

Aplicação

14:0 Lyso PC has been used to study its role in nerve growth factor (NGF)-induced mitogen-activated protein kinase (MAPK) and serine/threonine-protein kinase akt-1 signals in rat pheochromocytoma PC12 cells.
14:0 Lyso PC may be used:
  • as a component of detergent micelle to analyze the secondary structure of the purified twin-arginine translocation (Tat) membrane protein (TatCd) by circular dichroism (CD)
  • for the synthesis of three monofluorinated dimyristoylphosphatidylcholines (F-DMPC′s), such as 2F-DMPC, 12F-DMPC and 14F-DMPC
  • as a component of dry lipid film for the synthesis of palladium (Pd)-pyrolipid theranostic nanoparticles (PdPL-NPs) and manganese-pyrolipid surface-enhanced Raman scattering (SERS) NPs (MnPL-NPs)

Embalagem

20 mL Clear Glass Screw Cap Vial (855575P-1g)
20 mL Clear Glass Screw Cap Vial (855575P-500mg)
5 mL Amber Glass Screw Cap Vial (855575P-200mg)
5 mL Amber Glass Screw Cap Vial (855575P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

geralmente comprado junto com este produto

Nº do produto
Descrição
Preços

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Sigma-Aldrich

P2663

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Sigma-Aldrich

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Nano-enabled SERS reporting photosensitizers
Farhadi A, et al.
Theranostics, 5(5), 469-469 (2015)
Structure analysis of the membrane protein TatCd from the Tat system of B. subtilis by circular dichroism
Nolandt OV, et al.
Biochimica et Biophysica Acta - Biomembranes, 1788(10), 2238-2244 (2009)
Evaluation of the effect of fluorination on the property of monofluorinated dimyristoylphosphatidylcholines
Gagnon MC, et al.
Organic & Biomolecular Chemistry, 12(28), 5126-5135 (2014)
Lysophosphatidylcholine enhances NGF-induced MAPK and Akt signals through the extracellular domain of TrkA in PC12 cells
Itakura A, et al.
FEBS Open Bio, 3, 243-251 (2013)
Norimichi Nagano et al.
Biological & pharmaceutical bulletin, 42(11), 1926-1935 (2019-11-07)
Elevated intraocular pressure (IOP) is the major cause of glaucoma, which is the second leading cause of blindness. However, current glaucoma treatments cannot completely regulate IOP and progression of glaucoma. Our group recently found that autotaxin (ATX) activity in human
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