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Documentos Principais

791268P

Avanti

DTPA-BSA (Gd)

DTPA-bis(stearylamide) (gadolinium salt), powder

Sinônimo(s):

(diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt); Gd-DTPA-BSA

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About This Item

Fórmula empírica (Notação de Hill):
C50H94GdN5O8
Número CAS:
186796-30-5
Peso molecular:
1050.56
Número MDL:
MFCD22570234
Código UNSPSC:
12352211
NACRES:
NA.25

Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 100 mg (791268P-100mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand 791268P

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

Descrição geral

DTPA-BSA (Gd) (diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt)) is an amphiphilic molecule with paramagnetic property.

Aplicação

DTPA-BSA (Gd) (diethylenetriaminepentaacetic acid)-bis(stearylamide) (gadolinium salt)) has been used:
  • in the preparation of nontargeting (NT) gadolinium peptide amphiphile micelles (PAMs) for the magnetic resonance imaging (MRI) of atherosclerotic lesions
  • as a MRI agent in the preparation of lipid-like nanoparticles (LLNs) for small interfering RNA (siRNA) encapsulation
  • as a MRI agent in the preparation of paramagnetic saposin C and dioleylphosphatidylserine (SapC-DOPS) vesicles for imaging glioblastoma multiforme (GBM) tumors

Ações bioquímicas/fisiológicas

Gd-DTPA-BSA is useful as magnetic resonance imaging (MRI) agent and the gadolinium ion enables the generation of bright images by lowering the longitudinal relaxation time.

Embalagem

5 mL Amber Glass Screw Cap Vial (791268P-100mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

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Certificados de análise (COA)

Lot/Batch Number

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Geralda A F van Tilborg et al.
Bioconjugate chemistry, 17(3), 741-749 (2006-05-18)
Apoptosis, or programmed cell death, plays an important role in the etiology of a variety of diseases, including cancer and myocardial infarction. Visualization of apoptosis would allow both early detection of therapy efficiency and evaluation of disease progression. To that
Sang Pil Yoo et al.
ACS omega, 1(5), 996-1003 (2016-12-06)
The leading causes of morbidity and mortality globally are cardiovascular diseases, and nanomedicine can provide many improvements including disease-specific targeting, early detection, and local delivery of diagnostic agents. To this end, we designed fibrin-binding, peptide amphiphile micelles (PAMs), achieved by
F Jasanada et al.
Bioconjugate chemistry, 7(1), 72-81 (1996-01-01)
In order to use the LDL receptor pathway to target radionuclides to cancer sites for imaging and diagnostic purposes, a labeling procedure of LDL with 111In using the DTPA-bis(stearylamide) (L) has been developed. This bifunctional ligand is intended to be
Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents
Luo X, et al.
Nanoscale, 9(4), 1575-1579 (2017)

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