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Key Documents

850458P

Avanti

16:0-18:2 PC

1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine, powder

Sinônimo(s):

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; PC(16:0/18:2(9Z,12Z))

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About This Item

Fórmula empírica (Notação de Hill):
C42H80NO8P
Número CAS:
Peso molecular:
758.06
Código UNSPSC:
51191904
NACRES:
NA.25

Ensaio

>99% (TLC)

forma

powder

embalagem

pkg of 2 × 100 mg (850458P-200mg)
pkg of 1 × 25 mg (850458P-25mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 850458P

tipo de lipídio

cardiolipins
phospholipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

Descrição geral

16:0-18:2 PC or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a glycerophospholipid, with substitution of palmitic acid and linolenic acid at sn-1 and sn-2 positions of the glycerol backbone, respectively.

Aplicação

16:0-18:2 PC or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine:
  • has been used in liposomes for standard cell-free translation
  • has been used in the extraction of serum lipids and in peroxisome proliferator-activated receptor-δ (PPAR-δ) assay
  • might be used to study the effects of phosphatidylcholines (PCs) on lubrication of damaged mesothelium

Embalagem

5 mL Clear Glass Sealed Ampule (850458P-200mg)
5 mL Clear Glass Sealed Ampule (850458P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids


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Visite a Biblioteca de Documentos

Francesca Bodega et al.
Respiratory physiology & neurobiology, 203, 116-120 (2014-08-17)
Effect of time and phosphatidylcholines (PCs) on lubrication of damaged mesothelium has been investigated. Marked increase in coefficient of kinetic friction (μ) of pleural specimens after mesothelial blotting and rewetting decreased by 23.4±3.5%, 41.8±3.8%, and 40.5±2.7% after 30min, 1h, and
Lindsay Kosack et al.
Scientific reports, 7(1), 11289-11289 (2017-09-14)
Lipid metabolism is increasingly being appreciated to affect immunoregulation, inflammation and pathology. In this study we found that mice infected with lymphocytic choriomeningitis virus (LCMV) exhibit global perturbations of circulating serum lipids. Mice lacking the lipid-sensing surface receptor triggering receptor
Giulia Coliva et al.
Molecules (Basel, Switzerland), 25(8) (2020-04-25)
Free radical driven lipid peroxidation is a chain reaction which can lead to oxidative degradation of biological membranes. Propagation vs. termination rates of peroxidation in biological membranes are determined by a variety of factors including fatty acyl chain composition, presence
Eikan Mishima et al.
Journal of the American Society of Nephrology : JASN, 31(2), 280-296 (2019-11-27)
Ferroptosis, nonapoptotic cell death mediated by free radical reactions and driven by the oxidative degradation of lipids, is a therapeutic target because of its role in organ damage, including AKI. Ferroptosis-causing radicals that are targeted by ferroptosis suppressors have not
Elitza S Sevova et al.
The Journal of biological chemistry, 285(27), 20580-20587 (2010-05-12)
The Trypanosoma brucei genome has four highly similar genes encoding sphingolipid synthases (TbSLS1-4). TbSLSs are polytopic membrane proteins that are essential for viability of the pathogenic bloodstream stage of this human protozoan parasite and, consequently, can be considered as potential

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