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Merck
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Key Documents

A50606

Sigma-Aldrich

6-Aminouracil

97%

Sinônimo(s):

4-Amino-2,6-dihydroxypyrimidine, 6-Amino-2,4-pyrimidinediol

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About This Item

Fórmula empírica (Notação de Hill):
C4H5N3O2
Número CAS:
Peso molecular:
127.10
Beilstein:
120491
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22

Nível de qualidade

Ensaio

97%

forma

powder

pf

≥360 °C (lit.)

cadeia de caracteres SMILES

Nc1cc(O)nc(O)n1

InChI

1S/C4H5N3O2/c5-2-1-3(8)7-4(9)6-2/h1H,(H4,5,6,7,8,9)

chave InChI

LNDZXOWGUAIUBG-UHFFFAOYSA-N

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificados de análise (COA)

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H Sladowska et al.
Acta poloniae pharmaceutica, 53(1), 39-46 (1996-01-01)
Synthesis of 6-substituted 2,4-dioxo-1,2,3,4,5,6,7,8-octahydropyrimido[4,5-d]pyrimidines [III-VI] obtained by cyclocondensation of 1-phenyl-6-aminouracil with formaline and the primary amines is described. Compounds III, V, VI in the Mannich reaction with secondary cyclic amines yield the corresponding 3-substituted N-aminomethyl derivatives VII-X. Some of them
Kyung Mee Kim et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(1-2), 65-70 (2008-12-17)
Uric acid (UA) can be directly converted to allantoin enzymatically by uricase in most mammals except humans or by reaction with superoxide. UA can react directly with nitric oxide to generate 6-aminouracil and with peroxynitrite to yield triuret; both of
María-Jesús Pérez-Pérez et al.
Mini reviews in medicinal chemistry, 5(12), 1113-1123 (2005-12-27)
Thymidine Phosphorylase (TPase) catalyses the reversible phosphorolysis of pyrimidine 2'-deoxynucleosides to 2-deoxyribose-1-phosphate and their respective pyrimidine bases, including the phosphorolysis of nucleoside analogues with important antiviral or anticancer properties. Moreover, TPase, identified also as the angiogenic platelet-derived endothelial cell growth
Christine Gersch et al.
Nucleosides, nucleotides & nucleic acids, 27(8), 967-978 (2008-08-13)
The 1980 identification of nitric oxide (NO) as an endothelial cell-derived relaxing factor resulted in an unprecedented biomedical research of NO and established NO as one of the most important cardiovascular, nervous and immune system regulatory molecule. A reduction in
K Hirota et al.
Nucleic acids symposium series, (37)(37), 59-60 (1997-01-01)
Inhibitors of thymidine phosphorylase (dThdPase) are expected to suppress the growth and metastasis of tumor cells by inhibition of angiogenesis and were designed by utilizing the three dimensional structure of the enzyme. 5-Substituted 6-aminouracils (5) and 7-substituted pyrrolo[2,3-d]pyrimidine-2,4-diones (6) were

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