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Merck
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Documentos Principais

764620

Sigma-Aldrich

Poly(D,L-lactide)

greener alternative

average Mn 10,000, PDI ≤1.2

Sinônimo(s):

PDLA, PLA, polyDL-lactide

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About This Item

Código UNSPSC:
12162002
NACRES:
NA.23

Formulário

solid

Nível de qualidade

atividade óptica

[α]/D 0°, c = 0.5% in chloroform

peso molecular

average Mn 10,000

características do produto alternativo mais ecológico

Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

prazo de degradação

<6 months

pf

287-293 °C

PDI

≤1.2

categoria alternativa mais ecológica

temperatura de armazenamento

2-8°C

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Descrição geral

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This is an enabling product that belongs to a family of high-performance bio-based polymers that are essential for developing efficient, low-cost, and environmentally friendly renewable energy solutions. Click here for more information.

Aplicação

Used in Drug Delivery including coating nanoparticles1. Can be end-group functionalizated2 or used as a macroinitiator/block precursor3.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Os clientes também visualizaram

Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

Artigos

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

Global Trade Item Number

SKUGTIN
764620-5G4061832923093

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