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38534

Sigma-Aldrich

Polylactic acid

Mw ~60,000

Sinônimo(s):

Poly(2-hydroxypropionic acid)

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About This Item

Número CAS:
26100-51-6
Número MDL:
MFCD00081867
Código UNSPSC:
12162002
NACRES:
NA.23

Formulário

solid

prazo de validade

limited shelf life, expiry date on the label

peso molecular

Mn ~30,000
Mw ~60,000

cadeia de caracteres SMILES

[O-]C(=O)C(O)C.[H+]

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)

chave InChI

JVTAAEKCZFNVCJ-UHFFFAOYSA-N

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Descrição geral

Polylactic acid(PLA) is a biodegradable polyester synthesized from lactic acid monomer via ring opening polymerization. Owing to its excellent thermal, mechanical and barrier properties, it is widely used in the field of tissue engineering, drug delivery, and orthopedic devices.

Aplicação

Polylactic acid can be used to prepare tubular scaffolds via the electrospinning method. These scaffolds are applicable in vascular tissue engineering.

It can be used to prepare PLA/polyvinyl alcohol wound dressing membrane through electrospinning and coating method. The coating of PLA improves the mechanical strength of nanofiber and acts as a protective layer to control the release of drug to the wound site.

It can also be used to synthesize free-standing, flexible ultra-thin PLA nanofilms which can act as a matrix for adhesion, spreading, and proliferation of skeletal muscle cells.

Características e benefícios

  • Biocompatibility
  • Lower toxicity
  • Low cost
  • Better encapsulation

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCK1816
BCCK1817
BCCJ8035
BCCJ8036
BCCJ3789

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Polyglycolide inherent viscosity 1.4dL/g

Sigma-Aldrich

457620

Polyglycolide

Poly(L-lactide) viscosity ~2.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

81273

Poly(L-lactide)

Poly(L-lactide) viscosity ~4.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

95468

Poly(L-lactide)

Tong Chen et al.
Carbohydrate polymers, 92(2), 1124-1132 (2013-02-13)
Core-shell structured multifunctional nanocarriers (NCs) of ZnO quantum dots-conjugated gold nanoparticles (Au NPs) as core and amphiphilic hyperbranched block copolymer as shell were synthesized for targeted anticancer drug delivery. The amphiphilic hyperbranched block copolymer contained poly(l-lactide) (PLA) inner arm and
L Pearce McCarty et al.
The Journal of bone and joint surgery. American volume, 95(6), 507-511 (2013-02-15)
A variety of complications associated with the use of poly-L-lactic acid (PLLA) implants, including anchor failure, osteolysis, glenohumeral synovitis, and chondrolysis, have been reported in patients in whom these implants were utilized for labral applications. We report on a large
Zhenxing Fan et al.
Environmental technology, 33(19-21), 2369-2374 (2013-02-12)
Biological nitrate removal using wheat straw and polylactic acid (PLA) as both carbon source and biofilm support was investigated. The results showed that biofilm could develop on the surface of wheat straw within 15 d, the denitrification rate was 0.067
Discussion: Autologous fat grafting and injectable dermal fillers for human immunodeficiency virus-associated facial lipodystrophy: a comparison of safety, efficacy, and long-term treatment outcomes.
David Teplica
Plastic and reconstructive surgery, 131(3), 507-509 (2013-03-01)
Huan Zhou et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2302-2310 (2013-03-19)
Fibrous bionanocomposites consisting of amorphous magnesium phosphate (AMP) nanospheres and polylactic acid (PLA) were fabricated by electrospinning. There are two important signatures of this paper. First, AMP, as an alternative to well-known calcium phosphate (CaP) materials, is added to PLA
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In this article, we discuss issues critical to successful application of the electrospinning technique, including control of individual nanofibers to form secondary structures and assembly of nanofibers into 3D architectures.

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