69893

2-Morpholinoethyl isocyanide

≥98.0% (GC)

• Sinônimo(s): 4-(2-Isocyanoethyl)morpholine, MEI
• Fórmula empírica (Notação de Hill): C₇H₁₂N₂O
• Número CAS: 78375-48-1
• Peso molecular: 140.18
• Beilstein: 4666990
• Número MDL: MFCD00040506
• Código UNSPSC: 12352100
• ID de substância PubChem: 57652222
• NACRES: NA.22

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥98.0% (GC)
• Formulário: liquid
• índice de refração: n20/D 1.469
• p.e.: 72-73 °C/0.7 mmHg (lit.)
• densidade: 1.017 g/mL at 20 °C (lit.)
• grupo funcional: amine; ether; isonitrile
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [C-]#[N+]CCN1CCOCC1
• InChI: 1S/C7H12N2O/c1-8-2-3-9-4-6-10-7-5-9/h2-7H2
• chave InChI: MFRZPLYKVDHOSN-UHFFFAOYSA-N

Descrição

Aplicação

2-Morpholinoethyl isocyanide can be used for the synthesis of:

• Nitrogen acyclic carbene (NAC) complexes to be used as catalysts for the synthesis of phenol and hydration of alkynes.
• Variety of imidazo[1,2-a]pyridines and α-acylaminoamides by Ugi condensation reaction.
• 2-Aminobenzoxazoles and 3-aminobenzoxazines having important therapeutic activities.

It can also be used as a ligand in bis-cyclometalated iridium complexes for the organic light emitting diodes (OLEDs).

Outras notas

Potent coupling reagent for peptide synthesis giving higher yields and less racemization than DCCI; Reagent used in a Passerini-like reaction to alpha-hydroxy amides

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301 + H311 + H331,H315,H319,H335
• Declarações de precaução: P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 230.0 °F - closed cup
• Ponto de fulgor (°C): 110 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter