D125806

N,N-Diisopropylethylamine

ReagentPlus^®, ≥99%

• Sinônimo(s): N-Ethyldiisopropylamine, DIPEA, Ethyldiisopropylamine, ‘Hünig’s base’
• Fórmula linear: [(CH₃)₂CH]₂NC₂H₅
• Número CAS: 7087-68-5
• Peso molecular: 129.24
• Número CE: 230-392-0
• Número MDL: MFCD00008868
• Código UNSPSC: 12352100
• ID de substância PubChem: 329798682
• NACRES: NA.21

Propriedades

• pressão de vapor: 31 mmHg ( 37.7 °C)
• Nível de qualidade: 200
• linha de produto: ReagentPlus^®
• Ensaio: ≥99%
• forma: liquid
• índice de refração: n20/D 1.414 (lit.)
• pb: 127 °C (lit.)
• pf: <−50 °C (lit.)
• densidade: 0.742 g/mL at 25 °C (lit.)
• cadeia de caracteres SMILES: CCN(C(C)C)C(C)C
• InChI: 1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3
• chave InChI: JGFZNNIVVJXRND-UHFFFAOYSA-N

Descrição

Descrição geral

N,N-Diisopropylethylamine, also known as Hünig′s base, is a sterically hindered amine. It is a non-nucleophilic base commonly employed for substitution reactions. It acts as an activator for chiral iridium N, P ligand complexes, which can be utilized in the hydrogenation of α, β-unsaturated nitriles. The influence of varying concentration of N,N-diisopropylethylamine on the synthesis of olvanil in the presence of lipase catalyst has been investigated.

Aplicação

N,N-Diisopropylethylamine may be used in the synthesis of mannosylated ovalbumin peptides.

Proton scavenger used in peptide coupling, enolboration, Pd(0)-catalyzed alkoxycarbonylation of allyl phosphates and acetates, and as a catalyst in vinyl sulfone synthesis.

Informações legais

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS02,GHS06,GHS05,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H225,H302,H318,H331,H335,H411
• Declarações de precaução: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 49.1 °F
• Ponto de fulgor (°C): 9.5 °C