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465178

Sigma-Aldrich

2,2′-(Ethylenedioxy)diethanethiol

95%

Sinônimo(s):

1,2-Bis(2-mercaptoethoxy)ethane, 3,6-Dioxa-1,8-octane-dithiol

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About This Item

Fórmula linear:
HSCH2CH2OCH2CH2OCH2CH2SH
Número CAS:
14970-87-7
Peso molecular:
182.30
Beilstein:
1901671
Número CE:
239-044-2
Número MDL:
MFCD00015873
Código UNSPSC:
12352103
ID de substância PubChem:
24870251
NACRES:
NA.23

Nível de qualidade

200

Ensaio

95%

índice de refração

n20/D 1.509 (lit.)

pb

225 °C (lit.)

densidade

1.12 g/mL at 25 °C (lit.)

cadeia de caracteres SMILES

SCCOCCOCCS

InChI

1S/C6H14O2S2/c9-5-3-7-1-2-8-4-6-10/h9-10H,1-6H2

chave InChI

HCZMHWVFVZAHCR-UHFFFAOYSA-N

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Descrição geral

2,2′-(Ethylenedioxy)diethanethiol (EDT) is a dithiol based cross-linker that can be used for thiolene photopolymerization and to obtain crosslinked polymeric films.
3,6-dioxa-1,8-octanedithiol is non volatile in nature.

Aplicação

3,6-dioxa-1,8-octanedithiol (DODT) was used for cleaving peptides in the study to develop synthetic peptide serology to treat chronic chagas disease. DODT may be used to develop non-malodorous scavenger in Fmoc-based peptide synthesis.
EDT can be crosslinked with unsaturated olive oil to form a photoinduced eco-friendly film through renewable sources. It can be used in the synthesis of bioanode for the fabrication of a biofuel cell (BFC) for glucose sensing application. It may also be used for other applications such as improving the optical properties of gold nanoclusters (AuNCs) and the development of bio-mediated synthetic polyester.

Pictogramas

Skull and crossbonesEnvironment
GHS06,GHS09

Palavra indicadora

Danger

Frases de perigo

H301,H332,H410

Classificações de perigo

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

285.8 °F

Ponto de fulgor (°C)

141 °C

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
SHBP1306
SHBN8778
SHBN2375
SHBM6656
SHBM4882

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Andrea D'Ambrogio et al.
Nucleic acids research, 37(12), 4116-4126 (2009-05-12)
Nuclear factor TDP-43 has been reported to play multiple roles in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. From a structural point of view, TDP-43 is a member of the hnRNP protein family whose structure includes two RRM domains
Insights into the effect of surface ligands on the optical properties of thiolated Au 25 nanoclusters.
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Crosslinkable polyesters based on monomers derived from renewable lignin.
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A Teixeira et al.
Protein and peptide letters, 9(5), 379-385 (2002-10-09)
We have synthesized a random group of peptides and performed cleavages using various cleavage cocktails including 3,6-dioxa-1,8-octanedithiol (DODT). Purity of the peptides was compared to that obtained with standard protocols for cleavage using RP-HPLC and Maldi-Tof mass spectrometry. We show
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