298891

(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone

99%

• Sinônimo(s): (4R,5S)-4-Methyl-5-phenyl-2-oxazolidinone
• Fórmula empírica (Notação de Hill): C₁₀H₁₁NO₂
• Número CAS: 77943-39-6
• Peso molecular: 177.20
• Beilstein: 1211705
• Número MDL: MFCD00010845
• Código UNSPSC: 12352005
• ID de substância PubChem: 24858003
• NACRES: NA.22

Propriedades

• Ensaio: 99%
• Formulário: solid
• atividade óptica: [α]18/D +168°, c = 2 in chloroform
• pureza óptica: ee: 98% (GLC)
• pf: 121-123 °C (lit.)
• cadeia de caracteres SMILES: C[C@H]1NC(=O)O[C@H]1c2ccccc2
• InChI: 1S/C10H11NO2/c1-7-9(13-10(12)11-7)8-5-3-2-4-6-8/h2-7,9H,1H3,(H,11,12)/t7-,9-/m1/s1
• chave InChI: PPIBJOQGAJBQDF-VXNVDRBHSA-N

Descrição

Aplicação

Evan′s chiral auxiliary (4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone reacts with carboxylic acids to produce corresponding acyl derivatives in the presence of a diisopropylcarbodiimide reagent. It can also employed in the preparation of N-sulfinyloxazolidinone reagent (chiral sulfinyl transfer reagent), which reacts with nucleophiles such as Grignard reagents, enolates, and metalated amides to produce the chiral sulfoxides, sulfinate esters, and sulfonamides.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)