192724

Diisobutylaluminum hydride solution

25 wt. % in toluene

• Sinônimo(s): DIBAL, DIBAL-H
• Fórmula linear: [(CH₃)₂CHCH₂]₂AlH
• Número CAS: 1191-15-7
• Peso molecular: 142.22
• Beilstein: 4123663
• Número MDL: MFCD00008928
• Código UNSPSC: 12352001
• ID de substância PubChem: 24851561
• NACRES: NA.22

Propriedades

• Formulário: liquid
• Nível de qualidade: 200
• adequação da reação: reagent type: reductant
• concentração: 25 wt. % in toluene
• densidade: 0.846 g/mL at 25 °C
• cadeia de caracteres SMILES: CC(C)C[AlH]CC(C)C
• InChI: 1S/2C4H9.Al.H/c2*1-4(2)3;;/h2*4H,1H2,2-3H3;;
• chave InChI: AZWXAPCAJCYGIA-UHFFFAOYSA-N

Descrição

Descrição geral

Diisobutylaluminum hydride solution is a strong reducing agent used to convert arylpropiolate esters to their propargyl alcohols.

Diisobutylaluminum hydride reducing agent is commonly used for the reduction of an ester to aldehyde.

Aplicação

Diisobutylaluminum hydride solution (25 wt. % in toluene) has been used for the reduction of imides:

• N

• -(cis-2-Vinylcyclohexyl)succinimide to 1-(cis-2-vinylcyclohexyl)-5-hydroxy-2-pyrrolidinone
• N-(But-4-en-1-y1)-2(E)-(carbethoxymethylidene)-5-oxo-pyrrolidine to N-(but-4-en-1-yl)- 2(E)-(carbethoxymethylidene)-5-hydroxypyrrolidine
• N-(Hept-1-en-4-y1)-2(E)-(carbethoxymethylidene)-5-oxo-pyrrolidine to N-(hept-1-en-4-y1)-2(E)-(carbethoxymethylidene)-5-hydroxypyrrolidine
• N-(cis-2-Vinylcyclohexyl)-2-(carbethoxymethylidene)-5-oxopyrrolidine to rel-(3aR,SS,5aS,SaR)-1( E)-(carbethoxymethylidene)-5-(formyloxy)dodecahydropyrrolo[1,2-a]quinoline

Used in Pd-catalyzed reductive debromination of secondary alkyl bromides. O-Debenzylation and ring opening of perbenzylated furanosides. Convenient in situ generation of HZrCp₂Cl from ZrCp₂Cl₂ and DIBAL-H.

Embalagem

The 25 g Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

View returnable container options.

Informações legais

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Informações de segurança

• Pictogramas: GHS02,GHS08,GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H225,H250,H260,H304,H314,H336,H361d,H373,H412
• Declarações de precaução: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P370 + P378
• Classificações de perigo: Aquatic Chronic 3 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 Inhalation - STOT SE 3 - Water-react 1
• Órgãos-alvo: Central nervous system
• Perigos de suplementos: EUH014
• Código de classe de armazenamento: 4.2 - Pyrophoric and self-heating hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 39.2 °F - closed cup
• Ponto de fulgor (°C): 4 °C - closed cup
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter