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Merck
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Documentos Principais

182028

Sigma-Aldrich

Poly(ethylene oxide)

average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor

Sinônimo(s):

Polyethylene oxide, PEO

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About This Item

Fórmula linear:
(-CH2CH2O-)n
Número CAS:
Número MDL:
Código UNSPSC:
12352104
ID de substância PubChem:
NACRES:
NA.23

Nome do produto

Poly(ethylene oxide), average Mv 600,000 (nominal), powder

Formulário

powder

Nível de qualidade

peso molecular

average Mv 600,000 (nominal)

contém

200-500 ppm BHT as inhibitor

viscosidade

4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

temperatura de transição

Tm 65 °C

Ω-final

hydroxyl

α-final

hydroxyl

aplicação(ões)

battery manufacturing

cadeia de caracteres SMILES

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

chave InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Descrição geral

Poly(ethylene oxide)(PEO) is a high molecular weight, non-ionic water-soluble polymer. It forms agel on hydration and shows good swelling capacity. PEO polymers are non-toxicand widely used in drug delivery systems to enhance drug solubility.

Aplicação

Poly(ethylene oxide) can be used to prepare:
  • Bioabsorbable and injectable hydrogels for sustained drug release.
  • PEO/graphene oxide composite electrolyte membrane for fuel cells.
  • Poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. Losartan potassium encapsulated (PEO-b-PCL) copolymer can be used as a drug carrier.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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D D Smyth et al.
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Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
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Artigos

In this article, we discuss issues critical to successful application of the electrospinning technique, including control of individual nanofibers to form secondary structures and assembly of nanofibers into 3D architectures.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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