All Photos(4)

D8821

Sigma-Aldrich

Dextran from Leuconostoc mesenteroides

average mol wt 60,000-76,000

Linear Formula:
(C6H10O5)n
CAS Number:
EC Number:
MDL number:
NACRES:
NA.25

Quality Level

biological source

bacterial (Leuconostoc mesenteroides)

form

powder

optical activity

[α]20/D 190 to 201 °, c = 2% (w/v) in water

mol wt

average mol wt 60,000-76,000

storage temp.

2-8°C

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Packaging

10, 50, 100, 500 g in poly bottle

Application

Use of dextrans as long and hydrophilic spacer arms improves the performance of immobilized proteins acting on macromolecules.

Biochem/physiol Actions

Dextran is a branched glucan composed of linear a(1→6) linked glucose units and a (1→3) link initiated branches. Dextran ranges in size from 10,000 to 150,000 Kd. Dextrans are used in many applications as volume extenders, stabilizers, matrix components, binding platforms, lubricants and physical structure components.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Certificate of Analysis

Certificate of Origin

Yang Yang et al.
Biochimica et biophysica acta, 1840(1), 288-293 (2013-10-01)
Abnormal adhesion of red blood cells (RBCs) to vascular endothelium is often associated with reduced levels of sialic acids on RBC membranes and with elevated levels of pro-adhesive plasma proteins. However, the synergistic effects of these two factors on the
Zhiyang Li et al.
Journal of biomedical nanotechnology, 9(11), 1945-1949 (2013-09-26)
For reducing the steric hindrance and nonspecific binding of the target DNA, the dextran was used as molecular arms to be immobilized on the surface of magnetic nanoparticles (MNPs). Magnetic separation was used in preparation of dextran-MNPs (DMNPs). Aspartic acid
Marisa A Gallicchio et al.
Biochimica et biophysica acta, 1833(12), 2922-2932 (2013-06-12)
Chronic hyperglycaemia during diabetes leads to non-enzymatic glycation of proteins to form advanced glycation end products (AGEs) that contribute to nephropathy. We describe AGE uptake in LLC-PK1 and HK2 proximal tubule cell lines by macropinocytosis, a non-specific, endocytic mechanism. AGE-BSA
Boon M Teo et al.
Biochimica et biophysica acta, 1830(10), 4838-4847 (2013-07-03)
Liposomes have gained immerse attention in the field of drug delivery as carriers of therapeutic molecules. Their modification with a polymer either to make them stealth (e.g. using PEG) and/or more stable (e.g. using poly(dopamine) (PDA)) is a crucial aspect
M H Hemmelder et al.
The Journal of laboratory and clinical medicine, 132(5), 390-403 (1998-11-21)
Fractional dextran clearances have been extensively used to study glomerular size selectivity. We report on an analysis of different laboratory procedures involved in measuring fractional dextran clearances. The deproteinization of plasma samples by 20% trichloroacetic acid (TCA) revealed a protein

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