31390

Dextran from Leuconostoc spp.

M_r ~70,000

• Synonym(s): DEXTRAN 70
• Linear Formula: (C₆H₁₀O₅)_n
• CAS Number: 9004-54-0
• EC Number: 232-677-5
• MDL number: MFCD00130935
• NACRES: NA.25

Properties

• form: powder
• Quality Level: 200
• mol wt: M_r ~70,000
• loss: ≤7% loss on drying
• absorption: ≤0.05 at 375 nm in H₂O at 10%
• storage temp.: room temp

Description

General description

Dextran is an extracellular bacterial polymer of D-glucopyranose. It primarily consists of α-(1→6) linkage in the main chain and a variable amount of α-(1→2), α-(1→3), α-(1→4) branched linkages.

Application

Dextran from Leuconostoc spp. has been used:

• for the isolation of islets from pancreatic tissue by centrifugation
• as a component of Earle′s bicarbonate buffer for placental perfusion
• for the isolation of rat brain microvessels

Packaging

25, 100, 500 g

Biochem/physiol Actions

Dextran is a, which is commercially used as a drug, particularly as a blood plasma volume expander. It is used as an adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Sephadex, a cross-linked dextran is broadly used for the separation and purification of protein. In the food industry, dextran found its use as a thickener for jam and ice cream. It inhibits the crystallization of sugar, thereby enhancing moisture retention. This helps in maintaining the flavor and appearance of various food items.

Other Notes

Enhances immunoprecipitation sensitivity

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves