E7750
commercial grade
powder
110-115 °C (lit.)
H2O: ≤100 mg/mL
−20°C
Cl.CCN=C=NCCCN(C)C
1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H
FPQQSJJWHUJYPU-UHFFFAOYSA-N
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Danger
Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK 3
Not applicable
Not applicable
dust mask type N95 (US), Eyeshields, Gloves
Enter Lot Number to search for Certificate of Analysis (COA).
Enter Lot Number to search for Certificate of Origin (COO).
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
It means that it is the grade of N-(3-Dimethylaminopropyl)-N´-ethylcarbodiimide (EDAC) hydrochloride that was commercially available at the time we purchased it. This product is not assayed for purity. If you need a high purity EDAC, consider Product No. 03450.
Yes.
Yes. Nosaki, S., Effects of amounts of additives on peptide coupling mediated by a water-soluble carbodiimide in alcohols. J. Peptide Res., 54(2), 162-167 (1999). This paper describes using the E7750 along with 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine (HOOBt) and 1-hydroxy-7-azabenzotriazole (HOAt) for enhancement of peptide coupling.
The two compounds most likely to appear in EDAC as trace impurities are 3-dimethylaminopropylamine and N-(3-dimethylaminopropyl)-N'-ethylurea as a result of synthesis (intermediate) and degradation (moisture or coupling reaction), respectively.
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