N2513
NGF-β from rat
recombinant, expressed in Sf21 cells, lyophilized powder, suitable for cell culture
Synonim(y):
Nerve Growth Factor-β from rat
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About This Item
Polecane produkty
pochodzenie biologiczne
rat
Poziom jakości
rekombinowane
expressed in Sf21 cells
Próba
≥97% (SDS-PAGE)
Postać
lyophilized powder
siła działania
0.15-3.00 ng/mL EC50
opakowanie
pkg of 0.1 mg
metody
cell culture | mammalian: suitable
zanieczyszczenia
endotoxin, tested
rozpuszczalność
water: soluble 0.1 g/L at 20 °C
numer dostępu UniProt
temp. przechowywania
−20°C
informacje o genach
rat ... NGF(4803)
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Opis ogólny
NGFβ (nerve growth factor β) is a protein involved in signal transduction, and expressed by multiple tissues such as placenta, urothelium and bladder smooth muscle cells. It is a neurotrophin and belongs to the NGF family.
Zastosowanie
NGF-β from rat is used for the following applications:
- In the preparation of DMEM medium (for the cultivation and differentiation of PC12 cells)
- Western blotting analysis
- For the preparation of differentiation medium (it is prepared from DMEM, in which NGF-β is one of the components)
- In cell culture and treatment (for neuronal differentiation)
- In the preparation of stock solution
Działania biochem./fizjol.
NGFβ (nerve growth factor β) is essential for the differentiation and survival of neurons. It also plays a key role in the development and maintenance of nervous system. It is also involved in angiogenesis, and facilitates tumorigenesis such as, oral, breast and prostate cancers. It has potential as marker for the diagnosis of interstitial cystitis/painful bladder syndrome (IC/PBS) and overactive bladder (OAB), and might also aid in determining the therapy for the same. It might be involved in changes in placental function, as NGF signaling is influenced by antenatal depression and selective serotonin reuptake inhibitor (SSRI) treatment.
Postać fizyczna
Lyophilized from a 0.2 μm filtered solution in PBS and 1 M NaCl containing 50 μg of bovine serum albumin per 1 μg of cytokine
Komentarz do analizy
The biological activity is measured in a cell proliferation assay using the factor-dependent human erythroleukemic cell line, TF-1.
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Kod klasy składowania
13 - Non Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
Certyfikaty analizy (CoA)
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