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Merck

A9731

Sigma-Aldrich

Albumin human

recombinant, expressed in rice, lyophilized powder, suitable for cell culture, low endotoxin, ≥96% (SDS-PAGE)

Synonim(y):

Cellastim S, rHSA, rHSA

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About This Item

Wzór empiryczny (zapis Hilla):
C2936H4624N786O889S41
Numer CAS:
Masa cząsteczkowa:
66471.53
Numer MDL:
Kod UNSPSC:
12352202
eCl@ss:
42010201
NACRES:
NA.25

pochodzenie biologiczne

human

Poziom jakości

rekombinowane

expressed in rice

Próba

≥96% (SDS-PAGE)

Postać

lyophilized powder

masa cząsteczkowa

monomer ~67 kDa

metody

cell culture | mammalian: suitable

zanieczyszczenia

≤1 EU/mg protein

numer dostępu UniProt

temp. przechowywania

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

Klucz InChI

QYSGYZVSCZSLHT-UHFFFAOYSA-N

informacje o genach

human ... ALB(213)

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Zastosowanie

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Działania biochem./fizjol.

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Cechy i korzyści

Cellastim is a well defined, animal-free recombinant human albumin (rHA). Designed for cell culture applications, Cellastim is a powerful media supplement that outperforms plasma-derived human albumin, bovine serum albumin, and other sources of recombinant human albumin. Cellastim delivers consistent performance, not the variability associated with hydrolysates and extracts. Cellastim is ideally suited for use in cell culture media for Chinese Hamster Ovary (CHO), hybridoma, VERO, stem cells and primary cells.

Advantages
  • Eliminates animal-derived additives
  • Safe and regulatory friendly
  • Proven effective in enhancing stem cell growth in embryonic, mesenchymal, neural, cardiac, liver, kidney, keratinocyte and fibroblast stem cell lines
  • Maintains stem cells in an undifferentiated state
  • Eliminates coating of culture plates for adherent cell lines
  • Provides well-defined and consistent stem cell medium

Komentarz do analizy

Assayed by SDS-PAGE

Inne uwagi

1). Patent Rights
EP2230311
U.S. Patent No. 10,618,951
U.S. Patent No. 10,981,974
U.S. Patent No. 11,492,3892.
2). Registered Trademark Rights
U.S. Reg. 5,696,531
International Reg. 1,456,207
To view more information on Cellastim download the Cellastim Brochure, Cellastim CHO Poster, and Cellastim hybridoma Poster.
View more information on human serum albumin.

Informacje prawne

Cellastim is a trademark of InVitria
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)


Certyfikaty analizy (CoA)

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Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Junfeng Zhu et al.
Journal of pharmaceutical and biomedical analysis, 134, 100-107 (2016-11-28)
Danhong injection (DHI) is a widely used Chinese medicine injection (CMI) for the clinical treatment of cardiovascular and cerebrovascular diseases. In this study, a simple and efficient in vitro method based on ultrafiltration LC-MS and molecular modeling has been developed
Yongjia Fan et al.
ACS biomaterials science & engineering, 3(8), 1510-1518 (2016-08-14)
The development of platforms for the expansion and directed differentiation of human pluripotent stem cells (hPSCs) in large quantities under xeno-free conditions is a key step toward the realization of envisioned stem cell-based therapies. Microcarrier bioreactors afford great surface-to-volume ratio
D Moreno et al.
Theriogenology, 84(7), 1053-1060 (2015-08-19)
The aim of this study was to develop an in vitro embryo culture medium without either fetal calf serum or BSA, using various growth factors and cytokines (GFs-CYKs; IGF-I, IGF-II, bFGF, LIF, GM-CSF, TGF-β1, and PDGF-BB), and other molecules with
Wireeya Chawjiraphan et al.
MethodsX, 7, 101114-101114 (2020-11-17)
A simple and sensitive graphene oxide-mediated fluorescence quenching aptasensor is developed to quantify albuminuria in urine samples. The developed aptasensor used the specific target binding property of aptamer and fluorescence quenching property of graphene oxide to determine the concentration of
Yasuhiro Kawai et al.
PloS one, 13(5), e0196655-e0196655 (2018-05-26)
Serum albumin is the major intravascular antioxidant. Though oxidative stress plays an important role in the pathophysiology of Immunoglobulin A nephropathy (IgAN), the association between serum albumin and the progression of IgAN is not entirely understood. This retrospective cohort study

Produkty

This page segues to comprehensive insights on how serum albumin and other important cell culture components affect the performance of serum-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of albumin. These insights may also be applied to ex vivo and tissue engineering applications.

Lipid Induced Insulin Resistance

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