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Kluczowe dokumenty
A9135
Ethyl arachidonate
≥98.5% (GC), liquid
Synonim(y):
5,8,11,14-Eicosatetraenoic acid ethyl ester, Arachidonic acid ethyl ester
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About This Item
Wzór empiryczny (zapis Hilla):
C22H36O2
Numer CAS:
Masa cząsteczkowa:
332.52
Numer MDL:
Kod UNSPSC:
12352211
Identyfikator substancji w PubChem:
NACRES:
NA.25
Polecane produkty
pochodzenie biologiczne
fungus
Poziom jakości
Próba
≥98.5% (GC)
Formularz
liquid
grupa funkcyjna
ester
typ lipidu
omega FAs
Warunki transportu
ambient
temp. przechowywania
−20°C
ciąg SMILES
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC
InChI
1S/C22H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h8-9,11-12,14-15,17-18H,3-7,10,13,16,19-21H2,1-2H3/b9-8-,12-11-,15-14-,18-17-
Klucz InChI
SNXPWYFWAZVIAU-GKFVBPDJSA-N
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Działania biochem./fizjol.
Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, contraction, chemotaxis, and cell proliferation, differentiation and apoptosis. AA has been demonstrated to bind to the α subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane.
Opakowanie
Sealed ampule.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves
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