PHR1256

Abacavir sulfate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonim(y): Abacavir sulfate, {(1S, 4R)-4-[2-Amino-6- (cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol}
• Wzór empiryczny (zapis Hilla): C₂₈H₃₆N₁₂O₂ · H₂SO₄
• Numer CAS: 188062-50-2
• Masa cząsteczkowa: 670.74
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to Ph. Eur. Y0001561; traceable to USP 1000408
• rodzina API: abacavir
• Certyfikat analizy: current certificate can be downloaded
• metody: HPLC: suitable; gas chromatography (GC): suitable
• Zastosowanie: pharmaceutical (small molecule)
• Format: neat
• temp. przechowywania: 2-30°C
• ciąg SMILES: [S](=O)(=O)([O-])[O-].[n+]6(c7nc(nc(c7[nH]c6)NC8CC8)N)[C@@H]5C[C@@H](C=C5)CO.[n+]2(c3nc(nc(c3[nH]c2)NC4CC4)N)[C@@H]1C[C@@H](C=C1)CO
• InChI: 1S/2C14H18N6O.H2O4S/c2*15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21;1-5(2,3)4/h2*1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19);(H2,1,2,3,4)/t2*8-,10+;/m11./s1
• Klucz InChI: WMHSRBZIJNQHKT-FFKFEZPRSA-N

Opis

Opis ogólny

Abacavir sulfate belongs to the class of human immunodeficiency virus (HIV) medicines called nucleoside reverse transcriptase inhibitors, with antiretroviral activity against HIV.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Abacavir sulfate may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-peformance liquid chromatography technique and spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAC3642 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H317,H319,H341,H351,H361
• Zwroty wskazujące środki ostrożności: P202 - P261 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Klasyfikacja zagrożeń: Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable